An Autopsy Case of Malignant Ameloblastoma in the Maxilla : A case study
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概要
- 論文の詳細を見る
An autopsy case of malignant ameloblastoma in a 64-year-old Japanese woman is presented, which started as a benign ameloblastoma with plexiform and follicular patterns, and transformed into a malignant histology with atypical and mitotic tumor cells in the course of several recurrences. An autopsy revealed several relatively large metastases in the lungs bilaterally consisting of malignant ameloblastoma and intracranial invasion of malignant tumor cells to the left temporal lobe. Immunohistochemical staining of proliferating cell nuclear antigen (PCNA) demonstrated a significant increase in the proliferative activity of neoplastic cells between the primary tumor and two recurrent ones (P < 0.01, Newman-Keul's test). This data provides evidence of malignant transformation in a benign ameloblastoma in the course of multiple recurrences. Immunostaining of PCNA may be useful in determining the possibility of malignant transformation in recurrent cases of ameloblastoma.
- 特定非営利活動法人日本臨床口腔病理学会の論文
- 1999-06-20
著者
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Hatakeyama Setsuko
Department of Oral Pathology, School of Dentistry, Iwate Medical University
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Satoh Masanobu
Department of Oral Pathology, School of Dentistry, Iwate Medical University
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Satoh Masanobu
Department Of Oral Pathology School Of Dentistry
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Satoh Masanobu
Department Of Oral Pathology School Of Dentistry Iwate Medical University:department Of Periodontolo
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Satoh Masanobu
Department Of Oral Pathology Iwate Medical University School Of Dentistry
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Hatakeyama S
Department Of Oral Pathology School Of Dentistry Iwate Medical University
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Hatakeyama Setsuko
Department Of Oral Pathology Iwate Medical University School Of Dentistry
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Nakamura Yaeko
The First Department of Oral and Maxillofacial Surgery, School of Dentistry, Iwate Medical Universit
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Miyate Hiroki
The First Department of Oral and Maxillofacial Surgery, School of Dentistry, Iwate Medical Universit
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Kudo Keigo
The First Department of Oral and Maxillofacial Surgery, School of Dentistry, Iwate Medical Universit
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Kudo Keigo
The First Department Of Oral And Maxillofacial Surgery School Of Dentistry Iwate Medical University
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Nakamura Yaeko
The First Department Of Oral And Maxillofacial Surgery School Of Dentistry Iwate Medical University
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Miyate Hiroki
The First Department Of Oral And Maxillofacial Surgery School Of Dentistry Iwate Medical University
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