2. トレハロースと血管内皮保護物質を含む細胞外液型臓器保存液new ET-Kyoto液の開発と臨床応用(第49回低温生物工学会研究報告)

概要

論文の詳細を見る
Although organ transplantation is established as a therapeutic procedure for various terminal organ dysfunctions, there are many unsolved problems such as shortage of donors and primary graft failure. A more reliable organ preservation solution could resolve these problems. Therefore, we have developed new ET-Kyoto solution characterized by extracellular type ion composition, non-reducing disaccharide of trehalose, and vascular endothelial protective agents (dibutyryl cAMP, nitroglycerin, N-acetyl cysteine). We confirmed the superior efficiency of the solution in canine lung transplantation and have applied it to clinical lung transplantation at Kyoto University Hospital since April 2002.
低温生物工学会の論文
2003-12-30