ラット骨格筋中のアンゼリン, カルノシン含量に及ぼすビタミンB_1,B_2,B_6又はパントテン酸欠乏食の影響

概要

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The experiments were designed to study the effect of some watersoluble vitamin deficiencies in Wistar strain rats upon the anserine and carnosine contents in gastrocnemius muscle. Male rats (body weight 70〜80g) were divided into 5 groups and fed on each vitamin deficient and control diet for 4 weeks. The anserine, carnosine, protein, DNA, RNA, free N^π-methylhistidine, free histidine, free β-alanine and creatinine contents in the muscle were measured. Body weight and food intake were also measured. By the vitamin B_1 deficiency, an increase of anserine and a remarkable increase of carnosine were observed. By the vitamin B_2 or vitamin B_6 deficiency, no effect on anserine content and a remarkable decrease of carnosine were recognized. And free β-alanine decreased. By the pantothenic acid deficiency, no effects on anserine and carnosine were observed. The free histidine and N^π-methylhistidine levels were not affected by the above vitamin deficiencies.
日本ビタミン学会の論文
1977-10-25