EREMOTHECIUM ASHBYIIのビタミンB_2生産に関する研究 : (XL)汚染防止試験

概要

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Experiments for preventing contamination were conducted with several antiseptics or antibiotics in order to complete safely the submerged culture or Eremothecium ashbyii for industrial production of riboflavin. The results obtained are as follows : 1) Bacillus subtilis group, frequently found as contaminants, was suppressed by the addition of 20 ppm of 2-(5-nitro)-furfural semicarbazone plus 5 ppm of 2-(5-nitro)-furylacrylyl amide, but some or the heat sensitive bacteria among putrifactive organisms grew under the same condition. Citrinin was found not to be used because of its marked inhibitory effect on Eremothecium ashb ii. 2) The tests for the effects of fungi, producing antifungal substances showed that the filtrates from fungal cultures inhibited rather the growth of Er. ashbyii than acted on contaminants.
日本ビタミン学会の論文