小児期のリポ酸代謝にかんする研究 : (II)離乳期および成熟期シロネズミのリポ酸代謝におよぼす食餌組成の影響

概要

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Studies were made on the urinary excretion of α-lipoic acid and its content of blood serum, kindney and liver tissue, using mature and weaning rats, fed on the low-protein diet (casein 5 %) and standard diet (casein 18%). In the low-protein fed mature rats, the α-lipoic acid levels were low as compared with the control. In weaning rats, the serum levels and hepatic contents decreased but renal contents were rather increased. The hepatic content of α-lipoic acid decreased most remarkably in weaning rats of protein deficiency. The α-lipoic acid contents in liver tissue were low in young rats fed on the trypthophan or lysine deficient diet. Those results suggest that appropriate intake of protein and well-balanced amino-acid in diet are required for the maintenance of normal metabolic process of α-lipoic acid.
日本ビタミン学会の論文
1964-04-25