高齢入院患者のビタミンB_1およびB_2栄養状態の実態 : 総合ビタミン剤長期連続投与の影響 : 高齢者における総合ビタミン剤長期服用効果 : ビタミンB_1,B_2

概要

論文の詳細を見る
In a series of studies on thiamin and riboflavin status in elderly, the influence of a long-term daily administration of multivitamin tablets containing 10 mg of TTFD (thiamin tetrahydrofurfuryl disulfide) and 7 mg of riboflavin was investigated on 17 elderly patients admitted in two hospitals for long terms and 20 young healthy adults (control). In both groups of elderly subjects and young adults, average blood thiamin levels were in the state of marginal thiamin deficiency before the administration of multivitamin tablets. After a long-term administration of multivitamin tablets, blood thiamin levels of the both groups increased to normal range. At 8 days after the discontinuance of multivitamin administration, the blood thiamin levels of elderly group decreased below the normal range, but those of young adult group stayed within normal range. It was clarified that erythrocyte transketolase activities and TPP effects were insensible index as compared to blood thiamin levels. On the other hand, almost no marginal riboflavin deficiency of the both groups was observed as indicated by blood riboflavin levels, erythrocyte glutathione reductase activities and FAD effects.
日本ビタミン学会の論文
1995-02-25