三次元心磁図計測に基づく伝導障害患者の波形解析

概要

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We carried out a 3D vector measurement of magneto-cardiograms (MCGs) of normal subjects and a patient with a right bundle branch block (RBBB), using a 3D second-order gradiometer connected to 39-channel SQUIDs, which can detect the magnetic field components perpendicular to the chest wall (Bz) and tangential to the chest wall (Bx, By) simultaneously. In order to compare the propagation pathway of the excitation in the heart for normal subjects and a patient with RBBB, a source estimation to the QRS complex was performed using the single-equivalent-current-dipole (ECD) method. It was found that, in both the normal subjects and the patient with RBBB, the ECD traced nearly the same pathway from the onset of the ORS complex to 50 ms (R-wave). But, for 60 to 150 ms, the trajectories of the ECD location in the patient with RBBB, which moved from the left to the right ventricle at a depth of about 4.5 to 7.5 cm from the body surface, clearly differed from those of the normal subjects, which stayed at the center of the heart. These differences were also confirmed by visual inspection of the movement of the extreme value of By in isofield contour maps.
社団法人日本磁気学会の論文
2001-04-15