妊孕能温存手術が奏効した未分化胚細胞腫の3症例

概要

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Pure ovarian dysgerminoma, a rare tumor accounts for approximately 2% of all ovarian malignancies. During these 20 years, three patients with pure ovarian dysgerminoma were treated at our institution. All patients underwent initial surgery: unilateral salpingo-oophorectomy alone in 1 patient, unilateral salpingo-oophorectomy followed by the combination of cisplatin, vinblastine, and bleomycin (PVB) in 1 patient, and unilateral salpingo-oophorectomy followed by the combination of bleomycin, etoposide, and cisplatin (BEP) in 1 patient. Three pregnancies have occurred in 1 patient with surgery alone. She had two full-term pregnancies. The other two patients had irregular or absent menses during chemotherapy but regained normal menstrual function promptly after chemotherapy. Median follow-up time was 70 months (range, 29 to 261 months). All patients have remained continuously disease-free with maintenance of normal reproductive function.
山口大学医学会の論文
2003-10-31