Single Nucleotide Polymorphisms of Cardiac Na^+ Channel Gene SCN5A : Allelic Prevalence in Brugada Syndrome and Their Biophysical Properties

スポンサーリンク

概要

• 論文の詳細を見る
• 社団法人日本循環器学会の論文
• 2003-03-01

著者

• Yokoshiki Hisashi

  Department Of Cardiovascular Medicine Hokkaido University Graduate School Of Medicine

• Makita Naomasa

  Japanese Brugada Multicenter Registry By The Minister Of Health Labour And Welfare National Cardiova

• Makita Naomasa

  Deaprtment Of Cardiovascular Medicine Hokaido University Graduate School Of Medicine

• Sasaki Koji

  Sohen Central Hospital

• Sasaki Kohji

  Department Of Cardiovascular Medicine Hokkaido University Graduate School Of Medicine

• Nakazawa Makoto

  Pediatric And Lifelong Congenital Cardiology Institute Southern Tohoku General Hospital

• Kitabatake Akira

  Deaprtment of Cardiovasular Medicine,Hokkaido University Graduate School of Medicine

• Sasaki Koji

  Deaprtment of Cardiovascular Medicine, Hokaido University Graduate School of Medicine

• Yokoi Hisataka

  Deaprtment of Cardiovascular Medicine, Hokaido University Graduate School of Medicine

• Yokoi Hisataka

  Department Of Cardiovascular Medicine Hokkaido University Graduate School Of Medicine

• Yokoi Hisataka

  Deaprtment Of Cardiovascular Medicine Hokaido University Graduate School Of Medicine

• Makita Naomasa

  Department Of Cadiovascular Medicine Hokkaido University Graduate School Fo Medicine

関連論文

• Pleomorphic ventricular tachycardia originating from Purkinje fiber network of left anterior fascicle
• Discharge use of angiotensin receptor blockers provides comparable effects with angiotensin-converting enzyme inhibitors on outcomes in patients hospitalized for heart failure
• Effects of Atrial Fibrillation on Long-Term Outcomes in Patients Hospitalized for Heart Failure in Japan : A Report From the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD)
• Anemia is an Independent Predictor of Long-Term Adverse Outcomes in Patients Hospitalized With Heart Failure in Japan : A Report From the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD)
• Characteristics and Outcomes of Hospitalized Patients With Heart Failure and Reduced vs Preserved Ejection Fraction : A Report From the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD)
• PJ-571 Multiple Mechanisms underlie Long QT Syndrome by the Change of Amino Acid R259 in the Intracellular S4-S5 Linker of KCNQ1(PJ096,Arrhythmia, Others (Clinical/Pathophysiology) 4 (A),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The
• State-Dependent Blocking Actions of Azimilide Dihydrochloride (NE-10064) on Human Cardiac Na^+ Channels
• L-Cysteine Prevents Oxidation-Induced Block of the Cardiac Na^+ Channel Via Interaction With Heart-Specific Cysteinyl Residues in the P-Loop Region
• OE-389 Clinical Phenotype of Japanese LQT1 Form of Congenital Long QT Syndrome by Location and Coding Type From Japanese Multicenter Registry(Arrhythmia, diagnosis/Pathophysiology/EPS(02)(A),Oral Presentation(English),The 72nd Annual Scientific Meeting of
• Absence of a Trafficking Defect in R1232W/T1620M, a Double SCN5A Mutant Responsible for Brugada Syndrome
• ファロー四徴症児の無酸素発作予防のためのカテーテル前投薬におけるペチジンの有用性について : 後方視的検討および前方視的無作為検討の結果から
• 1 Molecular Basis for Low Penetrance in the Long QT Syndrome(Meet the Expert 7 (ME7) (A) : Issues on Sudden Cardiac Death)(Special Program)
• Discharge use of angiotensin receptor blockers provides comparable effects with angiotensin-converting enzyme inhibitors on outcomes in patients hospitalized for heart failure
• CHARACTERISTICS OF CARDIAC FUNCTION DURING EXERCISE IN PATIENTS WITH TA AFTER FONTAN'S OPERATION : Doppler, RI : I : 48 Annual Scientific Meeting, Japanese Circulation Society
• ELECTROPHYSIOLOGICAL STUDIES IN PATIENTS WITH ATRIOVENTRICULAR DISCORDANCE : PROCEEDINGS OF THE 47th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY : Electrophysiology (I)
• OE-133 Novel intrinsic mechanism of the enhanced rate-dependant QT Shortening in R1623Q mutant of the LQT3 syndrome(Arrhythmia, Basic 4 (A) : OE16)(Oral Presentation (English))
• Mutation Site Dependent Variability of Cardiac Events in Japanese LQT2 Form of Congenital Long-QT Syndrome
• A Novel Mutation Associated With Jervell and Lange-Nielsen Syndrome in a Japanese Family
• OJ-009 A Common KCNE1 Polymorphism, D85N, is a Genetic Modifier of Long QT Syndrome(Arrhythmia, diagnosis/ Pathophysiology/ EPS(03)(A),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• A single mutation of cardiac sodium channel gene confers phenotypes of both Brugada and long QT syndromes
• Ion channel mutations and polymorphisms in Japanese patients with acquired long QT syndrome
• 3 Mutant KCNE3 Reduces Repolarizing Potassium Current And Causes Long QT Syndrome(Plenary Session 4 (PL-4) (A) New Scientific Approaches to QT Prolongation,Special Program,The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-009 N- And C-terminal KCNE1 Mutations Cause Distinct Phenotypes of Long QT Syndrome(Arrhythmia, diagnosis/pathophysiology/EPS-03, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PE-103 Clinical Phenotype of Japanese LQT3 Form of Congenital Long QT Syndrome by Location of Mutation from Japanese Multicenter Registry(PE018,Arrhythmia, Others (Clinical/Pathophysiology) (A),Poster Session (English),The 73rd Annual Scientific Meeting o
• FRS-117 Clinical and Electrocardiographic Characteristics of Japanese Probands with Brugada Syndrome with an SCN5A Mutation from Japanese Multicenter Registry(FRS24,Novel Mechanisms of Ventricular Arrhythmia (A),Featured Research Session (English),The 73r
• PJ-208 Impact of Frameshift Mutation and Nonsense-mediated mRNA Decay on Clinical Phenotype in LQT2 Form of Congenital Long QT Syndrome(Arrhythmia,diagnosis/Pathophysiology/EPS(13)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japa
• Congenital atrial standstill associated with coinheritance of a novel SCN5A mutation and connexin 40 polymorphisms
• FRS-119 Familial Isolated Cardiac Conduction Defect Associated with a Mutation in the Connexin40 Gene GJA5(FRS24,Novel Mechanisms of Ventricular Arrhythmia (A),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulat
• IS092 Ion channel gene mutations in acquired long QT syndrome
• IS086 Novel missense mutation in the Pore region of HERG gene in Long QT syndrome Patient
• OJ-426 Enhanced Temporal and Spatial Cycle Length Variability during Ventricular Fibrillation in Hypertrophic Cardiomyopathy(ECG/Body Surface Potential Mapping/Holter 6 (A) : OJ52)(Oral Presentation (Japanese))
• Increased cycle length variability during ventricular fibrillation : a novel predictor of arrhythmia recurrence
• Altered repolarization dynamics during premature stimulation in Brugada syndrome with inducible ventricular fibrillation
• Prevalence and Clinical Characteristics of Patients With Atrial Fibrillation : Analysis of 20,000 Cases in Japan
• A Case of Familial Ventricular Tachycardia
• PJ-413 Paced QRS Prolongation is Associated with the Vulnerability to Ventricular Fibrillation by the T-wave Shock(PJ070,Ventricular Arrhythmia (Clinical/Diagnosis/Treatment) 1 (A),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japane
• PJ-046 Genotype-Phenotype Correlations of KCNJ2 Mutations in Japanese Patients with Andersen-Tawil Syndrome(Arrhythmia, diagnosis/pathophysiology/EPS-10, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Impaired Activation of ATP-sensitive K^+ channels in Endocardial Cells from Left Ventricular Hypertrophy(Excitation-contraction Coupling/Ion Channel 1 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Risk Factors for Mortality and Morbidity in Patients with Cyanotic Congenital Heart Disease (Congenital Heart Disease/Kawasaki's Disease 2 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Arrhythmias Late After Repair of Tetralogy of Fallot : A Japanese Multicenter Study
• Effect of beraprost sodium on pulmonary vascular resistance in candidates for a Fontan procedure : A preliminary study
• An SCN5A Mutation Associated With Idiopathic Ventricular Fibrillation Alters The Na^+ Channel Pore Structure And Responses To Antiarrhythmic Drugs
• OE-081 Mechanistic Basis for the Pathogenesis of Long QT Syndrome Associated with a Common Splicing Mutation in KCNQ1 Gene(Arrhythmia, basic-1, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-190 A KCNE1 Single Nucleotide Polymorphism, D85N, Serves as a Modifier in Forme-fruste Type of Long QT syndrome(Genetics/Genetically engineered models/Gene therapy-3 (M) PJ32,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of t
• OJ-349 High Incidence of Cardiac Events for Long-QT Syndrome with Compound Mutations(Arrhythmia, diagnosis/pathophysiology/EPS-4 (A) OJ59,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-064 Age-Related Triggers for Life-Threatening Arrhythmia in Genotyped Long-QT Syndrome(Arrhythmia, diagnosis/pathophysiology/EPS-3 (A) OJ11,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• Genetic Analysis of PRKAG2 in a Family with Inherited Wolff-Parkinson-White Syndrome (Arrhythmia, Diagnosis/Pathophysiology/EPS 8 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Novel SCN5A mutation (Q55X) associated with age-dependent expression of Brugada syndrome presenting as neurally mediated syncope.
• Role of KCNQ1 in the Cell Swelling-Induced Enhancement of the Slowly Activating Delayed Rectifier K^+ Current
• Sensitive Method of Detecting Myocardial Ischemia During Dobutamine Stress Echocardiography : Assessment of Asynchrony in Early-Systolic Wall Motion
• Double SCN5A mutation underlying asymptomatic Brugada syndrome
• Single Nucleotide Polymorphisms of Cardiac Na^+ Channel Gene SCN5A : Allelic Prevalence in Brugada Syndrome and Their Biophysical Properties
• High-risk for Bradyarrhythmic Complications in Patients with Brugada Syndrome Caused by SCN5A Gene Mutations(Arrhythmia, Basic (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-602 Clinical Characteristics Associated with Mutation Sites in LQT2 Form of Congenital Long-QT Syndrome(Arrhythmia, basic-5 (A) PJ101,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• 5 Overlap Between LQT3 and Brugada Syndrome : Clinical Features in a Common Mutation and Underlying Biophysical Mechanisms(Plenary Session 4 (PL-4) (A) New Scientific Approaches to QT Prolongation,Special Program,The 72nd Annual Scientific Meeting of the
• Improvement of Myocardial Ischemia in the Areas with Chronic Total Tcclusion without MI after PCI Assessed by 99mTc-tetrofosmin SPECT(Nuclear Cardiology 8 (I), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• NORADRENALINE-INDUCED ALTERATIONS IN ADENYLATE CYCLASE SYSTEM OF RAT HEART MEMBRANES : Cardiovascular Drugs : 53 Annual Scientific Meeting, Japanese Circulation Society
• Increased P-Selectin Expression on Platelets and Decreased Plasma Thrombomodulin in Fontan Patients
• Aortic and Valvular Size in Patients with Aortic Regurgitation Long after Arterial Switch Operation in Transposition of the Great Arteries
• Genetic Polymorphisms and Arrhythmia Susceptibility(Genetics of Arrhythmias)
• Molecular Basis for the Phenotypic Variability of Cardiac Sodium Channelopathies(Ion Channels and Cardiac Arrhythmias : Current Understanding and Future, The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• PE-307 Left Ventricular Noncompaction Associated With Mutations in Cardiac Na Channel Gene SCN5A(Cardiomyopathy, basic/clinical-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OE-085 Genetic Factors Conferring Congenital Sick Sinus Syndrome in SCN5A Mutation Carriers(Arrhythmia, basic-1, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Nonreentrant atrioventricular nodal tachycardia due to triple nodal pathways manifested by radiofrequency ablation at coronary sinus ostium
• Quantitative Analysis of Aberrant Splicing Caused by a Splice-site Mutation in KCNQ1 Gene of a Patient with Long QT Syndrome (Genetics/Genetically Engineered Models (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Sustained Ventricular Tachycardia and Late Potentials after Repair of Tetralogy of Fallot(Congenital Heart Disease/Kawasaki's Disease 1 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• ALTERATIONS OF PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C AND PROTEIN KINASE C ACTIVITIES IN THE MYOCARDIUM OF SPONTANEOUSLY HYPERTENSIVE RATS (SHR) : Cardiomyopathy, Myocarditis : 53 Annual Scientific Meeting, Japanese Circulation Society
• -P163- PARTIAL PURIFICATION AND CHARACTERIZATION OF PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C IN RAT MYOCARDIUM
• 1 Genotype-Phenotypes Relations of SCN5A-Positive Brugada Syndrome(Brugada Syndrome:From Cell to Bedside,Plenary Session 2 (PL2) (A),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• Increased Cycle Length Variability during Ventricular Fibrillation in Patients with Cardiomyopathy
• SCN5A Gene Silencing by Adenovirus-mediated Short Interfering RNA Delivery in Neonatal Rat Ventricular Myocytes(Arrhythmia, Basic 2 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• EVALUATION OF LEFT VENTRICULAR FUNCTION IN PATIENTS AFTER JATENE PROCEDURE, A STUDY USING LEFT VENTRICULAR END-SYSTOLIC WALL STRESS-VELOCITY OF FIBER SHORTENING RELATION : Ventricular Function : 53 Annual Scientific Meeting, Japanese Circulation Society
• Guidelines for Diagnosis and Management of Cardiovascular Sequelae in Kawasaki Disease (JCS 2008) : Digest Version
• Aborted Sudden Cardiac Death Associated with Short QT Syndrome
• Enhanced sodium channel intermediate inactivation in Brugada syndrome
• Molecular and Biophysical Bases of Brugada Syndrome
• -0532-ALTERATIONS OF MEMBRANE PHOSPHOINOSITIDE METABOLISM IN THE HEART OF CARDIOMYOPATHIC SYRIAN HAMSTER BIO 14.6 (BIO)
• Body Mass Index Is an Independent Predictor of Long-Term Outcomes in Patients Hospitalized With Heart Failure in Japan : A Report Frown the Japanese Cardiac Registry of Hears Failure in Cardiology (JCARE-CARD)
• Immunonutritional effects during synbiotics therapy in pediatric patients with short bowel syndrome
• -0229-ALTERATIONS OF PHOSPHOLIPASE C (PLC) ISOZYME PATTERN IN THE AORTA OF SPONTANEOUSLY HYPERTENSIVE RATS (SHR)
• HEMODYNAMIC EFFECTS OF ISOPROTERENOL DURING EARLY STAGES OF MORPHOGENESIS, DIFFERENCE BETWEEN CHICK AND RAT EMBRYOS : Cardiovascular Drugs : 53 Annual Scientific Meeting, Japanese Circulation Society
• Afterload Mismatch, and Cerebral Intraventricular and Pulmonary Hemorrhage in Preterm Infants
• OE-284 Oxygen Causes Contraction of the Ductus Arteriosus By Decreasing Intracellular H_2O_2 Generation(Congenital Heart Disease/Kawasaki's Disease 1 (M) : OE35)(Oral Presentation (English))
• Arrhyhtmias in Postoperative Cyanotic Congenital Heart Disease : -Japanese Experience-(ALTAS-CHD Study)(Diagnosis and Management of Arrhythmias in Adults with Congenital Heart, The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Novel Strain Rate Index of Contractility Loss Caused by Mechanical Dyssynchrony : A Predictor of Response to Cardiac Resynchronization Therapy
• Predictors of Long-Term Adverse Outcomes in Elderly Patients Over 80 Years Hospitalized With Heart Failure : A Report From the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD)
• Guidelines for Risks and Prevention of Sudden Cardiac Death (JCS 2010) : Digest Version
• Loop Diuretic Use at Discharge Is Associated With Adverse Outcomes in Hospitalized Patients With Heart Failure : A Report From the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD)
• Mode of Death in Patients With Heart Failure and Reduced vs. Preserved Ejection Fraction : Report From the Registry of Hospitalized Heart Failure Patients
• Beta-Blocker Use at Discharge in Patients Hospitalized for Heart Failure Is Associated With Improved Survival
• Clinical and Genetic Features of Japanese Patient with Congenital Long QT Syndrome
• Novel SCN3B Mutation Associated With Brugada Syndrome Affects Intracellular Trafficking and Function of Nav1.5
• Strain Rate Dispersion Index Can Predict Changes in Left Ventricular Volume and Adverse Cardiac Events Following Cardiac Resynchronization Therapy
• Iodine-123-Metaiodobenzylguanidine Scintigraphy of Total Cardiac Adrenergic Denervation in Brugada Syndrome.
• Anticoagulation Management in the Perioperative Phase of Implantable Cardioverter Defibrillator Implantation
• Long-Term Survival in Implantable Cardioverter-Defibrillators (ICD) Leads Inserted by the Extrathoracic Introduction Technique
• Report of the American Heart Association (AHA) Scientific Sessions 2013, Dallas
• Novel SCN3B Mutation Associated Witt Brugada Syndrome Affects Intracellular Trafficking and Function of Nav1.5
• Anticoagulation Management in the Perioperative Phase of Implantable Cardioverter Defibrillator Implantation
• Strain Rate Dispersion Index Can Predict Changes in Left Ventricular Volume and Adverse Cardiac Events Following Cardiac Resynchronization Therapy

もっと見る 閉じる

スポンサーリンク