Chromosome-Wide Association Study of Disease-Related Polymorphisms for Myocardial Infarction

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概要

• 論文の詳細を見る
• 社団法人日本循環器学会の論文
• 2003-03-01

著者

• Yasunami Michio

  Department of Molecular Pathogenesis, Division of Medical Science, Medical Research Institute, Tokyo

• Kimura Akinori

  Department Of Diagnostic And Therapeutic Radiology Ehime University Graduate School Of Medicine

• Kimura Akinori

  Department Of Molecular Pathogenesis Medical Research Institute Tokyo Medical And Dental University

• Izumi Toru

  東京医科歯科大学 疾患生命科学研究部ゲノム多様性

• Kimura Akinori

  東京医科歯科大学難治疾患研究所 分子病態分野

• Hohda Shigeru

  Department of Molecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental Universit

• Izumi Toru

  Kitasato University School of Medicine

• Sasaoka Haishi

  Kitasato University

• Yasunami Michio

  Laboratory Of Genome Diversity School Of Biomedical Science Tokyo Medical And Dental University

• Kimura Akinori

  Medical Research Institute Tokyo Medical And Dental University

• Hohda Shigeru

  Department Of Cardiology Kitasato University School Of Medicine

• Kimura Akinori

  Department Of Molecular Pathogenesis Division Of Medical Science Medical Research Institute Tokyo Me

• Yasunami Michio

  Department Of Immunogenetics Institute Of Tropical Medicine (nekken) Nagasaki University

• Kimura Akinori

  Department Of Molecular Pathogenesis Division Of Adult Diseases Medical Research Institute Tokyo Med

関連論文

• Mutational Analysis of Fukutin Gene in Dilated Cardiomyopathy and Hypertrophic Cardiomyopathy(Molecular Cardiology)
• PJ-913 Radial strain as a possible parameter of the extent of the delayed-enhacement in patients with hypertrophic cardiomyopathy(MRI / MRA(04)(I),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-119 Synergistic Polymorphisms of Angiotensin Converting Enzyme and Endothelial Nitric Oxide Synthase and Cardiovascular Events in Patients with Hypertrophic Cardiomyopathy(Cardiomyopathy, basic / clinical(02)(M),Oral Presentation (Japanese),The 72nd An
• OJ-117 The effect of cibenzoline in patients with hypertrophic obstructive cardiomyopathy-Insights from changes In left ventricular regional-temporal heterogeneity(Cardiomyopathy, basic / clinical(02)(M),Oral Presentation (Japanese),The 72nd Annual Scient
• OE-037 Combined Analysis of Polymorphisms in Inflammation-Related Genes and Their Effects on Atrial fibrillation in Patients with Dilated Cardiomyopathy(Arrhythmia, diagnosis/Pathophysiology/EPS(01)(A),Oral Presentation(English),The 72nd Annual Scientific
• PE-212 T-182C Polymorphism of the Norepinephrine Transporter (SLC6A2) Gene and Cardiovascular Events in Patients with Dilated Cardiomyopathy(Cardiomyopathy, basic/clinical-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-053 Angiotensin-Converting Enzyme Insertion/Deletion Polymorphism Affects Left Ventricular Pressure Gradient Response to Cibenzoline in Patients with Hypertrophic Obstructive Cardiomyopathy(Cardiomyopathy, basic/clinical-2, The 71st Annual Scientific M
• OJ-052 Association between Endothelin-2 A985G Polymorphism and Atrial Fibrillation in Patients with Hypertrophic Cardiomyopathy(Cardiomyopathy, basic/clinical-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• FRS-085 Association between G674A Polymorphism of the Connexin 40.1 Gene and Atrial Fibrillation in Patients with Dilated Cardiomyopathy(Arrhythmia (clinical) ; Pathophysiology of Atrial Fibrillation, The 71st Annual Scientific Meeting of the Japanese Cir
• PJ-227 Small Left Ventricular Cavity as a Risk Factor for Drug Tolerance of Renin-Angiotensin System Inhibitors in Patients with Hypertension(Hypertension, clinical-9 (H) PJ38,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the
• Assessment of Myocardial Ischemia by Adenosine 5-triphosphate Stress Multi-slice Computed Tomography : Alternative to Stress Myocardial Perfusion Scintigraphy(Recent Advance in Cardiovascular Imaging Technique (X-ray/CT/MRI/DSA) (I), The 69th Annual Scien
• PJ-574 A Novel Missense Mutation (R2401H) in the Human Cardiac Ryanodine Receptor Gene (RyR2) in Patient with Catecholaminergic Polymorphic Ventricular Tachycardia(Arrhythmia, Basic and Diagnosis/Pathophysiology/EPS (A) : PJ96)(Poster Session (Japanese))
• PJ-616 Late Myocardial Enhancement at 64-Multislice Computed Tomography Compared with Magnetic Resonance Imaging(PJ103,CT/MRI (Myocardium) 2 (I),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• PE-415 Quantification of Myocardial Strain of Left Ventricle Using Myocardial Tagging at 3.0T(PE070,CT/MRI (Myocardium) (I),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese Circulation Society)
• DPE-054 Standardized Coronary 64-slice CT Angiography Using the Diluted Contrast Medium : Single Center Study(DPE09,CT/MRI (Coronary/Vascular) (I),Digital Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• Clinical Significance of T-Wave Alternans in Hypertrophic Cardiomyopathy
• Usefulness of Coronary Flow Analyses by Transthoracic Doppler Echocardiography after Percutaneous Coronary Intervention for Ostial Stenoses due to Takayasu's Arteritis : A Case Report
• PJ-707 Left ventricular twisting behavior in patients with hypertension : Analysis by two dimensional speckle tracking method(Hypertension, clinical(09)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-704 Possible Link Between Left Ventricular Systolic and Diastolic Dyssynchrony and Diastolic Function in Patients With Essential Hypertension(Hypertension, clinical(09)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circ
• PJ-531 Chronic Kidney Disease is Associated with Impaired Coronary Flow Velocity Reserve(Kidney/Renal circulation(07)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-418 A Novel Method for Measurement of Carotid Arterial Elastic Properties Using Two Dimensional Speckle Tracking Analysis(Atherosclerosis, clinical(11)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society
• PE-219 Visualization of the Left Ventricular Endocardial Surface by Virtual Cardioscopy Using ECG-gated Multi-slice Computed Tomography(CT/DSA-05, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-504 Functional alterations of TCAP mutations found in hypertrophic cardiomyopathy and dilated cardiomyopathy(Cardiomyopathy, Basic (M) : OJ62)(Oral Presentation (Japanese))
• OJ-083 KCNQ1 Mutation Causing Defective Channel Trafficking and Dominant-Negative Suppression Underlie Severe Phenotype of Congenital Long QT Syndrome(Arrhythmia, Basic 1 (A) : OJ10)(Oral Presentation (Japanese))
• The role of a common TNNT2 polymorphism in cardiac hypertrophy
• Mutations in a Hyperpolarization-activated Channel as the Molecular Basis of Ventricular Arrhythmia(Arrhythmia, Basic 4 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• An SCN5A Mutation Associated With Idiopathic Ventricular Fibrillation Alters The Na^+ Channel Pore Structure And Responses To Antiarrhythmic Drugs
• Mutational Analysis of Cardiac Ryanodine Receptor Genes (RyR2) in Patients with Catecholaminergic Polymorphic Ventricular Tachycardia and Arrhythmogenic Right Ventricular Cardiomyopathy(Arrhythmia, Basic 2 (A), The 69th Annual Scientific Meeting of the Ja
• FRS-026 HERG potassium channel regulated by phosphotyrosine kinase(Arrhythmia-Basic : Molecular and Genetic : Basis (A) : FRS4)(Featured Research Session (English))
• PJ-201 A Compound Heterozygous Mutation in KCNQ1 Associated with Long QT Syndrome(Arrhythmia, basic(05)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• Genetic Analysis of Dilated Cardiomyopathy : HLA and immunoglobulin genes may confer susceptibility : MOLECULAR ANALYSIS OF THE PATHOPHYSIOLOGY OF CARDIOMYPATHY
• Quantification of Regional Myocardial Blood Flow Using First-Pass Multidetector-Row Computed Tomography and Adenosine Triphosphate in Coronary Artery Disease
• PJ-831 Quantification of Regional Myocardial Blood Flow using First-Pass Multidetector-row Computed Tomography and Adenosine Triphosphate in Coronary Artery Disease(CT / DSA(11)(I),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanes
• 5 Current Status and Future Direction of Multi Detector-row Computed Tomography for the Integrated Management of Coronary Artery Disease(Symposium 14 (SY-14) (I) New Horizon of CT, MR and PET in Diagnostic Cardiac Imaging,Special Program,The 72nd Annual S
• FRS-090 Identification of a Novel Disease Gene for Hypertrophic Cardiomyopathy(FRS19,Genetic Abnormalities in Cardiac Hypertrophy and Cardiomyopathy (M),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Soc
• Short-Term Effect of Amiodarone on Inflammatory Markers and Left Ventricular Function in Patients with Advanced Heart Failure Receiving Carvedilol(Heart Failure, Clinical 5 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Thallium-201 Myocardial Scintigraphy for Prediction of Prognosis in Patients with Dilated Cardiomyopathy Treated with Beta-blocker(Nuclear Cardiology 2 (I), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Prognostic Impact of Myocardial Microvascular Integrity in Patients With Hypertrophic Cardiomyopathy(Echo/Doppler 16 (I), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Endothelial Nitric Oxide Synthase Polymorphism (Glu298Asp) on Cardiovascular Events for Patients with Hypertrophic Cardiomyopathy(Myocardial Disease, Cardiomyopathy and Myocarditis (M), The 69th Annual Scientific Meeting of the Japanese Circulation Societ
• PJ-595 Myocardial damage on Thallium-201 scintigraphy and prognosis in patients with dilated cardiomyopathy treated with beta-blocker(Cardiomyopathy, Clinical 7 (M) : PJ100)(Poster Session (Japanese))
• PJ-423 Increased Circulating Levels of Heart-Type Fatty Acid-Binding Protein in Patients with Hypertrophic Cardiomyopathy : its Relation to the Thallium-201 Perfusion Defects(Cardiomyopathy, Clinical 5 (M) : PJ71)(Poster Session (Japanese))
• PJ-121 Genetic Predisposition to Hypertension Versus Insulin Resistance as Risk Factors for Hypertensive Left Ventricular Hypertrophy(Hypertension, Clinical 2 (H) : PJ20)(Poster Session (Japanese))
• PE-274 Serum Marker of Angiogenesis and Myocardial Ultrasonic Tissue Characterization in Patients with Idiopathic Dilated Cardiomyopathy(Cardiomyopathy, Clinical 2 (M) : PE47)(Poster Session (English))
• Fine Structural Analysis of the Unique 5' Region of the Human COL1A2 Gene Containing Two Regions of Dinucleotide Repeats Adjacent to the Transcriptional Start Site
• A Novel Frameshift Mutation in C-Terminal Region of HERG
• Chromosome-Wide Association Study of Disease-Related Polymorphisms for Myocardial Infarction
• A Novel Disease Genes for Cardiomyopathy : Identification of a CAV3 Mutation and Its Functional Alteration
• Microarray-Based Identification of Three Candidate Genes for Human Heart Failure : From Dahl Rat Model to Human Genome
• Novel HERG mutations in long QT syndrome in Japan
• Identification of a novel HLA-linked susceptibility gene to Takayasu's arteritis
• Genetic risk factors for myocardial infarction in Japanese
• Identification of caveolin-3 mutation in familial cardiomyopathy
• Quantitative assessment of regional left ventricular wall thickness and thickening using 16 multidetector-row computed tomography : comparison with cine magnetic resonance imaging
• PJ-530 Advantages of 3.0T MRI Cardiac Imaging(MRI/MRA-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Analysis of the Higher-Order Structure of the Two Dinucleotide Repeat Regions That Enhance the Transcriptional Activity of the Human Type I Collagen α2 (COL1A2) Gene Promoter
• PJ-516 Sex Differences in the Relationship between G-protein Beta3 Subunit Gene C825T Polymorphism and Cardiovascular Events in Patients with Dilated Cardiomyopathy(Heart failure, clinical(18)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting
• Relations of Uric Acid to Demographic, Left Ventricular Geometric and Renal Variables in Patients with Essential Hypertension(Hypertension, Clinical 3 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• PE-280 Relations of Serum Matrix Metalloproteinases in the Coronary Sinus to Left Ventricular Performance in Patients with Nonischemic Dilated Cardiomyopathy(Cardiomyopathy, basic/clinical(04)(M),Poster Session(English),The 72nd Annual Scientific Meeting
• PE-092 A Link Between Plasma NT-proBNP in the Coronary Sinus and Left Ventricular Dyssynchrony in Patients with Nonischemic Dilated Cardiomyopathy(Heart failure, clinical(07)(M),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Ci
• PE-045 Preventive Effect of Oral Ascorbic Acid on Attenuation of Coronary Flow Reserve by Nitrate Withdrawal.(Coronary circulation, basic/clinical(02)(IHD),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• Genomic structure and eight novel exonic polymorphisms of the human N-cadherin gene
• PJ-617 Structural Analysis of SLMAP in Idiopathic Ventricular Fibrillation : A Novel Disease Gene for Brugada Syndrome?(Genetics/Genetically engineered models/Gene therapy-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Molecular Etiology and Pathogenesis of Hereditary Cardiomyopathy(Molecular Mechanisms)
• PJ-350 Assessment Of The Myocardial Perfusion Using MDCT(CT/DSA-09, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PE-144 Cardiac Functional Analysis with "One-beat Whole Heart Imaging" Using the 2nd Spec 256-MSCT(Cardiac function, basic/clinical-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-127 Coronary CT Angiography Using 256 MDCT(CT / DSA-04, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OE-372 Twisting Behavior in the Heart : Quantification by Novel "Twist Map" with 3T Cardiac Magnetic Resonance Imaging(MRI/MRA-1, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• FRS-074 Cardiac Physiology in Robust "Beat by Beat" Cardiac Imaging Using the 2nd Spec 256-multislice Computed Tomography(New Cardivascular Imaging by MDCT, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-800 Long-Term Effect of Low-Dose Amiodarone on Left Ventricular Function and Inflammatory Activity in Patients With Advanced Heart Failure Receiving Carvedilol(Heart failure, clinical-18, The 71st Annual Scientific Meeting of the Japanese Circulation S
• PJ-229 Acute Effect of Decrease in Wall Stress on Strain and Left Ventricle Twisting Motion Evaluated by 2D Speckle Tracking Imaging(Cardiac function, basic/clinical-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PE-375 Vascular-Coronary Coupling : Large Artery Stiffness is a Determinant of Coronary Flow Velocity Reserve(Atherosclerosis, clinical-08, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PE-329 Intraventricular Dyssynchrony in Patients with Hypertrophic Cardiomyopathy is Associated with the Degree of Asymmetrical Septal Hypertrophy(Echo/Doppler-11, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Mutation of ZASP causes alteration in the affinity to protein kinase C subtypes and associates with familial dilated cardiomyopathy
• Molecular Etiology of Idiopathic Cardiomyopathy in Asian Populations
• Association of HLA-DRB1 0803 and 1602 with the susceptibility to primary biliary cirrhosis
• PE-225 Usefulness of Automated Functional Imaging for Assessment of Left Ventricular Regional wall Motion in Patients with Myocardial Infarction(Echo/Doppler-10, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PE-216 Risk Stratification With a Combination of Matrix Metalloproteinase-3 and B-type Natriuretic Peptide in Patients With Non-ischemic Dilated Cardiomyopathy(Cardiomyopathy, basic/clinical-3, The 71st Annual Scientific Meeting of the Japanese Circulatio
• PE-160 Significance of the Distal to Proximal Coronary Flow Velocity Ratio by Transthoracic Doppler Echocardiography for Diagnosis of Coronary Artery Stenosis(Echo/Doppler-09, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PE-141 A Link Between Degree of Central Apnea and BNP Level in Patients with Cardiovascular Disease Combined with Sleep Disordered Breathing(Cardiac function, basic/clinical-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Does a Gene Polymorphism Predisposing to an Intermediate Phenotype Predict the Risk of Disease? : A Lesson From CETP, High-Density Lipoprotein-Cholesterol and Coronary Artery Disease
• 1 Contribution of human genome diversity to the pathogenesis of dilated cardiomyopathy(The Cause of Dilated Cardiomyopathy : Inflammation or Genetic,Controversy 2 (C-2) (M),Special Program,The 72nd Annual Scientific Meeting of the Japanese Circulation Soc
• FRS-032 Testicular hormone accelerates the develoment and progress of dilated cardiomyopathy in an animal model(Molecular Determinants for the Development of Cardiomyopathy(M),Featured Research Session,The 72nd Annual Scientific Meeting of the Japanese Ci
• Transmural Perfusion Gradient in Adenosine Triphosphate Stress Myocardial Perfusion Computed Tomography
• Contribution of Genetic Factors to the Pathogenesis of Dilated Cardiomyopathy : The Cause of Dilated Cardiomyopathy : Genetic or Acquired? (Genetic-Side)
• FRS-011 End-systolic Volume Index and Left Ventricular Torsion Determine the Left Ventricular Untwisting Rate : Evidence of Restoring Force(Cardiac Function "Ventricular Mechanics and Calcium Handling", The 71st Annual Scientific Meeting of the Japanese C
• Molecular Genetics of Hypertrophic Cardiomyopathy in Japan
• Application of Genomic Information in Cardiovascular Diseases(The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Molecular Etiologies of Cardiomyopathies(Clinical Approach to Personalized Medicine in Cardiovascular disease, The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• 1 Human genome diversity in etiology and pathogenesis of cardiomyopathy and heart failure(Perspectives of Genome-wide Study to Identify Genes Underlying Cardiovascular Diseases,Roundtable Discussion 10 (RT10) (M),The 70th Anniversary Annual Scientific Mee
• FRS-065 Overexpression of Cardiac Myosin Light Chain Phosphatase Small Subunit (hHS-M21) Lead to Hypertrophic Cardiomyopathy(Heart Failure, Cardiac Remodeling and Cardiomyopathy 1, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Coronary Endothelial Dysfunction and Non-Contrast Multidetector Computed Tomography
• Prevalence and Distribution of Sarcomeric Gene Mutations in Japanese Patients With Familial Hypertrophic Cardiomyopathy
• Genetic Screening and Double Mutation in Japanese Patients With Hypertrophic Cardiomyopathy
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• Association of HLA-A^*02:06 and HLA-DRB1^*04:05 with clinical subtypes of juvenile idiopathic arthritis
• A single nucleotide polymorphism in the 3'-untranslated region of MyD88 gene is associated with Buerger disease but not with Takayasu arteritis in Japanese
• Role of HCN4 channel in preventing ventricular arrhythmia
• HLA-DPB1 and NFKBIL1 may confer the susceptibility to chronic thromboembolic pulmonary hypertension in the absence of deep vein thrombosis
• Validation of eight genetic risk factors in East Asian populations replicated the association of BRAP with coronary artery disease
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