Enhancement of Hepatitis B Surface Antigen Production by Adenosine 5'-Monophosphate in Culture of Recombinant Chinese Hamster Ovary Cells(BIOCHEMICAL ENGINEERING)
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概要
- 論文の詳細を見る
Adenosine 5'-monophosphate was found effective in enhancing hepatitis B surface antigen (HBsAg) production in the culture of recombinant Chinese hamster ovary (CHO) cells, but it markedly inhibited cell growth. A culture strategy with periodical medium changes was established to increase HBsAg production and avoid the AMP-induced inhibition of cell growth. The enhanced energy supply might be one of the reasons for the increase in HBsAg production in the presence of AMP.
- 公益社団法人日本生物工学会の論文
- 2005-10-25
著者
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Zhang Yuanxing
State Key Laboratory Of Bioreactor Engineering East China University Of Science And Technology
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SUN XIANGMING
State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology
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Luo Weiwen
State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology
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Yi Xiaoping
State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology
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Luo Weiwen
State Key Laboratory Of Bioreactor Engineering East China University Of Science And Technology
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Yi Xiaoping
State Key Laboratory Of Bioreactor Engineering East China University Of Science And Technology
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Sun Xiangming
State Key Laboratory Of Bioreactor Engineering East China University Of Science And Technology
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- Enhancement of Hepatitis B Surface Antigen Production by Adenosine 5'-Monophosphate in Culture of Recombinant Chinese Hamster Ovary Cells(BIOCHEMICAL ENGINEERING)
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