Hollow Fiber Bioreactors with Internal Aeration Circuits
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概要
- 論文の詳細を見る
New hollow fiber bioreactors for aerobic culture were introduced and Aspergillus niger for citric acid production was cultivated as a model system. These reactors consisted of a bundle mixed of hydrophilic membranes for liquid nutrient transport and hydrophobic membranes for gaseous nutrient transport. The cells were successfully cultivated. However, the polymeric hollow fiber membranes were compressed and blocked by excessive fungal cell growth. Citric acid was produced with a high volumetric productivity compared with that of shake-flask fermentation, but the long-term operation was not successful due to a rapid decrease of the production rate.
- 社団法人日本生物工学会の論文
- 1990-03-25
著者
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Chang Ho
Department Of Electronic Engineering Dankook University
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Chung Bong
Genetic Engineering Research Insitute
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Chung Bong
Genetic Engineering Center Korea Institute Of Science And Technology
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Chang Ho
Department Of Chemistry Inje University
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Chang Ho
Department Of Chemical Engineering And Bio Process Engineering Research Center Korea Advanced Instit
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