New Antifungal and Cytotoxic Steroidal Saponins from the Bulbs of an Elephant Garlic Mutant
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概要
- 論文の詳細を見る
Saponins in bulbs of a mutant of elephant garlic were investigated, and three new steroidal saponins named yayoisaponins A-C were obtained together with the known dioscin and aginoside. Their structures, including the relative stereochemistry, were elucidated by spectral data interpretation, while the absolute stereochemistry of the sugar moieties was assigned on the basis of a chiral gas chromatographic analysis of the acid hydrolysates. Yayoisaponins A-C and aginoside exhibited not only in vitro cytotoxicity against P388 cells at 2.1 μg/ml, but also antifungal activity against Mortierella ramanniana at 10 μg/disk.
- 社団法人日本農芸化学会の論文
- 1998-10-23
著者
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SAITO Takeshi
Institute of Low Temperature Science, Hokkaido University
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Matsunaga Shigeki
Laboratory of Aquatic Natural Products Chemistry, Graduate School of Agricultural and Life Sciences,
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Fusetani Nobuhiro
Laboratory of Aquatic Natural Products Chemistry, Graduate School of Agricultural and Life Sciences,
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Fusetani Nobuhiro
Laboratory Of Aquatic Natural Products Chemistry Graduate School Of Agricultural And Life Sciences T
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Sata Noriko
Laboratory Of Aquatic Natural Products Chemistry Graduate School Of Agricultural And Life Sciences T
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Fusetani N
Univ. Tokyo Tokyo Jpn
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NISHIKAWA Hiroyuki
Institute for Consumer Healthcare, Yamanouchi Pharmaceutical Co. Ltd.
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TAKAMURA Shuichi
Institute for Consumer Healthcare, Yamanouchi Pharmaceutical Co. Ltd.
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Nishikawa Hiroyuki
Institute For Consumer Healthcare Yamanouchi Pharmaceutical Co. Ltd.
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Matsunaga Shigeki
Laboratory Of Aquatic Natural Products Chemistry Graduate School Of Agricultural And Life Sciences T
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Saito Takeshi
Institute Of Advanced Studies
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Matsunaga Shigeki
Laboratory Of Aquatic Natural Products Chemistry Graduate School Of Agricultural And Life Sciences T
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Takamura Shuichi
Institute For Consumer Healthcare Yamanouchi Pharmaceutical Co. Ltd.
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Saito Takeshi
Institute For Geothermal Sciences Kyoto University
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Saito Takeshi
Institute For Consumer Healthcare Yamanouchi Pharmaceutical Co. Ltd.
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