Immunopotentiating Activity of the Water-soluble Lignin Rich Fraction Prepared from LEM : The Extract of the Solid Culture Medium of Lentinus edodes Mycelia

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概要

• 論文の詳細を見る

• The water-soluble lignin in LEM (the extract of the solid culture medium of Lentinus edodes mycelia) has been known to have antiviral and immunopotentiating activities in vivo and in vitro. The water-soluble lignin rich fraction (JLS-18) was prepared from LEM using ultrafiltration and hydrophobic column chromatography. JLS-18 showed about 70 times higher antiviral activity than LEM in vitro. JLS-18 activated the cytotoxicity of NK cells and macrophages, and activated T cells in vitro. JLS-18 also induced interleukin 6 (IL-6) secretion from human leukocytes infected with Sendai virus in vitro. These data showed that JLS-18, the water-soluble rich fraction of LEM, had antiviral and immunopotentiating activities.

• 社団法人日本農芸化学会の論文
• 1997-11-23

著者

• Yamamoto Yoshiki

  Biochemistry Research Laboratories Jcr Pharmaceuticals Co. Ltd.

• Kono Keiko

  Biochemistry Research Laboratories Jcr Pharmaceuticals Co. Ltd.

• Shirono Hiroyuki

  Biochemistry Research Laboratories Jcr Pharmaceuticals Co. Ltd.

• OHASHI Yasuhiro

  Iizuka Institute, Noda Shokukin Kogyo Co., Ltd.

• OHASHI Yasunori

  Radiochemistry Research Laboratory, Shizuoka University

• Ohashi Y

  National Food Res. Inst. Ibaraki Jpn

関連論文

• Immunopotentiating Activity of the Water-soluble Lignin Rich Fraction Prepared from LEM : The Extract of the Solid Culture Medium of Lentinus edodes Mycelia
• Kinetic Analysis of the Effect of (-)-Epigallocatechin Gallate on the DNA Scission Induced by Fe(II)(Food & Nutrition Science)
• Detection of 2-Deoxy-D-ribose Radicals Generated by the Reaction with the Hydroxyl Radical using a Rapid Flow-ESR Method(Analytical Chemistry)

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