Predictors of Left Ventricular Remodeling in Patients With Acute Myocardial Infarction Participating in Cardiac Rehabilitation : Brain Natriuretic Peptide and Anterior Infarction
スポンサーリンク
概要
- 論文の詳細を見る
Background This study was designed to determine the factors influencing the development of left ventricular (LV) remodeling in patients participating in a comprehensive cardiac rehabilitation (CR) program after acute myocardial infarction (AMI), with special reference to exercise intensity and frequency. Methods and Results A total of 72 patients with AMI participated in CR consisting of exercise training of moderate intensity (heart rate reserve 40-60%) and education for 12 weeks. Plasma concentration of brain natriuretic peptide (BNP) was measured at the beginning and the end of CR. Echocardiography was performed before and 1 year after CR. An increase in LV end-diastolic dimension (delta-LVDd) from baseline was used as an index of remodeling. Delta-LVDd was significantly greater in patients with an anterior AMI than with other infarct locations (p<0.05) and correlated significantly with baseline BNP concentration (p<0.05). Delta-LVDd >5 mm occurred exclusively in patients with baseline BNP >150pg/ml. Variables representing the intensity and frequency of exercise training did not correlate with delta-LVDd. Conclusion In patients with AMI participating in CR, those having both anterior infarction and baseline BNP concentration >150pg/ml are at high risk for subsequent LV remodeling, whereas neither exercise intensity nor participation frequency in CR appears to be associated with LV remodeling.
- 社団法人日本循環器学会の論文
- 2004-02-20
著者
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GOTO Yoichi
Division of Cardiology, National Cardiovascular Center
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NONOGI Hiroshi
Division of Cardiology, National Cardiovascular Center
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Aihara Naohiko
Division of Cardiology, National Cardiovascular Center
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Sumida Hitoshi
Division of Cardiology, Kumamoto Red-Cross Hospital
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Sumida Hitoshi
Division Of Cardiology National Cardiovascular Center
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Aihara Naohiko
Division Of Cardiology Department Of Internal Medicine National Cardiovascular Center
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Nonogi Hiroshi
Division Of Cardiology And Emergency Medicine National Cardiovascular Center
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Sakuragi Satoru
Division of Cardiology, Department of Medicine, National Cardiovascular Center
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Yasumura Yoshio
Division of Cardiology, National Cardiovascular Center
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Takaki Hiroshi
Division of Cardiology, National Cadiovascular Center
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Takagi Shuichi
Division of Cardiology, Department of Medicine, National Cardiovascular Center
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Yasumura Yoshio
Division Of Cardiology National Cardiovascular Center
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Baba Takeshi
Division of Cardiology, National Cardiovascular Center
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Baba Takeshi
Division Of Cardiology National Cardiovascular Center
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Yasumura Yoshio
Laboratory Of Molecular Genetics National Cardiovascular Center
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Takiuchi Shin
Division Of Hypertension And Nephrology National Cardiovascular Center
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Goto Yoichi
Division Of Cardiology Department Of Medicine National Cardiovascular Center
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Tsutsui Hiroshi
Division Of Cardiology Department Of Medicine National Cardiovascular Center
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Takaki Hiroshi
Department Of Cardiovascular Dynamics National Cardiovascular Center Research Institute
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Sakuragi Satoru
Division Of Cardiology National Cardiovascular Center
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Takaki Hiroshi
Division Of Cardiology National Cardiovascular Center
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Takagi Shuichi
Division Of Cardiology National Cardiovascular Center
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Yoshimasa Yasunao
Department Of Atherosclerosiss And Diabetes National Cerebral And Cardiovascular Center
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Yasumura Yoshio
Division Of Cardiology Department Of Internal Medicine National Cardiovascular Center
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Susawa Takashi
Third Division Internal Medicine Faculty Of Medicine Kyoto University
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Tsutsui Hiroshi
Division Of Cardiovascular Medicine National Cardio Vascular Center
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Nonogi Hiroshi
Division Of Cardiac Care Unit Department Of Cardiovascular Medicine National Cerebral And Cardiovasc
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Sakuragi Satoru
Division Of Cardiology Iwakuni Clinical Center
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Sakuragi Satoru
Division Of Cardiology Department Of Medicine National Cardiovascular Center
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Yazaki Y
Department Of Gene Diagnostics And Therapeutics Research Institute International Medical Center Of J
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Aihara Naohiko
Division of Arrhythmia and Electrophysiology, Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
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Takaki Hiroshi
Division of Arrhythmia and Electrophysiology, Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
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