Coronary Flow-Pressure Relationship Distal to Epicardial Stenosis

スポンサーリンク

概要

• 論文の詳細を見る

• To assess the coronary flow velocity-pressure relationship distal to a stenosis, and to evaluate the influence of microvascular abnormalities on this relationship, coronary flow velocity and coronary pressure were measured simultaneously in 38 patients (42 vessels). The instantaneous peak coronary flow velocity was plotted against the simultaneous measured distal coronary pressure, and the slope of the relation in the phase of diastolic flow decrease was calculated as the flow-pressure slope index (FPSI) and the X-intercept of the slope was calculated as zero-flow pressure (Pzf). The slope of the curve increased from 2.0±2.6 to4.5±4.1 (p<0.001) and the X-intercept decreased from 42±16 to 27±13mmHg (p<0.001) after papaverine injection. After successful coronary intervention, Pzf increased from 23±10 to 35±11 (p<0.01) and FPSI decreased from 6.8±5.1 to 3.5±1.8 (p<0.05). Pzf was higher in patients with an old myocardial infarction. It is feasible to assess the relationship between coronary flow and pressure distal to a stenosis in the clinical setting, and the relationship may provide additional information regarding coronary microcirculation. Microvascular abnormalities may play an important role in the coronary flow-pressure relationship distal to stenosis. (Circ J 2003; 67: 525-529)

• 社団法人日本循環器学会の論文
• 2003-05-20

著者

• YAMASHINA Akira

  Second Department of Internal Medicine, Tokyo Medical University

• Takazawa Kenji

  Division Of Cardiology Hachioji Medical Center Tokyo Medical University Department Of Cardiology Tok

• Yamashina Akira

  Second Department Of Internal Medicine Tokyo Medical University

• Takeda Kazuhiro

  Second Department Of Internal Medicine Tokyo Medical University

• Tanaka Nobuhiro

  Division Of Cardiology Department Of Intenal Medicine Tokyo Medical University

• Tkazawa Kenji

  Division Of Cardiology Hachioji Medical Center Tokyo Medical University

• Takazawa Kenji

  Second Department Of Internal Medicine Tokyo Medical University

• Tanaka Nobuhiro

  Second Department of Internal Medicine, Tokyo Medical College

• Takazawa Kenji

  Division Of Cardiology Hachioji Medical Center Tokyo Medical University

• Takazawa Kenji

  Cardiology Of Hachioji Medical Center Tokyo Medical University

• SHINDO Naohisa

  Second Department of Internal Medicine, Tokyo Medical University

• Shindoh Naohisa

  Division Of Cardiology Department Of Intenal Medicine Tokyo Medical University

• Aikawa Masaru

  Second Department of Internal Medicine, Tokyo Medical University

• Amaya Kazutaka

  Second Department of Internal Medicine, Tokyo Medical University

• Kobori Yuichi

  Second Department of Internal Medicine, Tokyo Medical University

• Tanaka Nobuhiro

  2nd Department Of Internal Medicine Tokyo Medical University

• Tanaka Nobuhiro

  Second Department Of Internal Medicine Tokyo Medical College Hospital

• Takazawa Kenji

  Department Of Internal Medicine Tokyo Medical College Hospital

• Takazawa Kenji

  The Second Department Of Internal Medicine Tokyo Medical College

• Aikawa Masaru

  Second Department Of Internal Medicine Tokyo Medical University

• Kobori Yuichi

  Second Department Of Internal Medicine Tokyo Medical University

• Shido Naohisa

  Department Of Cardiology Tokyo Medical University

• Amaya Kazutaka

  Second Department Of Internal Medicine Tokyo Medical University

• Tanaka Nobuhiro

  Department Of Cardiology Tokyo Medical University

• Tanaka Nobuhiko

  The Second Department Of Internal Medicine Tokyo Medical University

• Takazawa Kenji

  Division Of Cardiology Hachioji Medical Center Tokyo Medical University Department Of Cardiology Tok

• Takazawa Kenji

  Division Of Cardiology Hachioji Medical Center Tokyo Medical University Department Of Cardiology Tok

• Takeda Kazuhiro

  The Second Department Of Internal Medicine Tokyo University

• Shindo Naohisa

  Second Department Of Internal Medicine Tokyo Medical University

関連論文

• Comparative Impact of Scintigraphic Parameters and B-Type Natriuretic Peptide for the Prediction of Major Cardiac Events in the QGS-Prognostic Value in the Elderly (Q-PROVE) Study
• Significance of the second peak of systolic blood pressure for identifying both high and low cardiovascular risk states
• Non-Invasive Vascular Function Tests: : Their Pathophysiological Background and Clinical Application
• Two Patients With Bepridil-Induced Interstitial Pneumonia
• Prognostic value of myocardial perfusion and ventricular function in a Japanese multicenter cohort study (J-ACCESS): the first-year total events and hard events
• PE-364 Preliminary Report of a Multicenter Cohort Study of Myocardial Viability Assessment by Gated^Tc-Sestamibi SPECT at Rest(Nuclear cardiology-5, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Surveillance study for creating the national clinical database related to ECG-gated myocardial perfusion SPECT of ischemic heart disease : J-ACCESS study design
• Prognostic Value of Post-Ischemic Stunning as Assessed by Gated Myocardial Perfusion Single-Photon Emission Computed Tomography : A Subanalysis of the J-ACCESS Study
• Prognostic value of myocardial perfusion SPECT images in combination with the maximal heart rate at exercise testing in Japanese patients with suspected ischemic heart disease: A sub-analysis of J-ACCESS
• Clinical Application of Photodynamic Therapy to Prevent Coronary Artery Stenting following Restenosis
• Enhanced expression of TNF-related-apoptosis-inducing ligand(TRAIL) and Tumor necrosis factor-α (TNF-α) in mononuclear cells after acute myocardial infarction
• Enhanced Expression of the Apoptosis Inducing Ligand TRAIL in Mononuclear Cells After Myocardial Infarction
• Anti-Atherosclerotic Effects of Tamoxifen in Cholesterol-fed Ovariectomized Rabbits
• Effects of Nicorandil on Aortic Input Impedance : A Comparative Study With Nitroglycerin
• P542 Analysis of Coronary Flow Velocity Components : Changes in the Component Pattern After Aortic Pressure Reduction
• P470 Ascending Aortic Pressure Can be Synthesized from Radial Arterial Pressure Using Generalized Transfer Function
• 0692 Wall Thickness and New Asynergy Durine Exercise Echocardiography
• The relationship between the Augmentation Index (AI) in the pressure pulse wave and aortic input impedance (AoImp)
• The Influence of Changes in Loading Patterns on Left Ventricular Relaxation in Humans
• TWO-DIMENSIONAL ECHOCARDIOGRAPHY(Ex-2DE)DURING EXERCISE OF PATIENTS WITH MULTIVESSEL ISCHEMIC HEART DESEASE
• UNDERESTIMATION OF EFFECT OF VASODILATOR AGENTS BY PERIPHERAL BLOOD PRESSURE MEASUREMENT;THE CAUSE AND STRATEGY
• THE INFLUENCE OF PERIPHERAL WAVE REFLECTION ON LEFT VENTRICULAR RELAXATION
• PJ-268 Quantitative analysis of the coronary artery stent's inside diameter in 16 Slice MDCT(X-ray/CT/MRI/DSA4 (I) : PJ45)(Poster Session (Japanese))
• OJ-253 Prognostic Value of the Double Product of Exercise Testing in Combination with Myocardial Perfusion Images : A Sub-Analysis of J-ACCESS(OJ43,Nuclear Cardiology (Coronary, Myocardium) (I),Oral Presentation (Japanese),The 73rd Annual Scientific Meeti
• OJ-172 Prognostic Value of the Heart Rate of Exercise Testing in Combination with Myocardial Perfusion SPECT Images : A Sub-Analysis of J-ACCESS(Nuclear cardiology(02)(I),Oral Presentation (Japanese),The 72nd Annual Scientific Meeting of the Japanese Circ
• IS149 Dose Coronary Collateral Recruitment Affect the Ischemic Preconditioning During Balloon Angioplasty? The Study With Pressure Guidewire
• IS148 Evaluation of acute recoil after percutaneous coronary intervention using coronary pressure measurement
• -296- THE DICROTIC NOTCH POSITION ON THE PRESSURE WAVE FORM AT THE BASE OF ASCENDING AORTA : Echo Cardiography : FREE COMMUNICATIONS(II) : PROCEEDINGS OF THE 51th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• Synergistic effect of smoking and blood pressure on augmentation index in men, but not in women
• Decrease of Fractional Flow Reserve Shortly After Percutaneous Coronary Intervention
• PJ-493 The Correlation between the Duke CAD Prognostic Index and Stress Myocardial SPECT(PJ083,Nuclear Cardiology (Coronary, Myocardium) 3 (I),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• Identification of multi-vessel coronary artery disease by quantitative SPECT with the measurements of absolute
• PE-260 Combination of neurohumoral factors and left atrial appendage function can predict outcome of electrical cardioversion of atrial fibrillation(Neurohumoral Factors 2 (H) : PE44)(Poster Session (English))
• Adjuvant Photodynamic Therapy with Local Photosensitizer Delivery Inhibits Restenosis after Coronary Angioplasty
• Coronary arterial spasm during adenosine myocardial perfusion imaging
• Do Eicosapentaenoic Acid Supplements Attenuate Age-Related Increases in Arterial Stiffness in Patients with Dyslipidemia? : A Preliminary Study
• Is Stress Myocardial Scintigraphy More Effective Than Fractional Flow Reserve Using Pressure Wire for Deciding Indication for Percutaneous Coronary Intervention?
• PJ-546 The Evaluation of Augmentaion Index and Blood Pressure for Aorta and Radial Artery(Hypertension, clinical-8 (M) PJ92,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• 1 Diagnostic Imaging of Vulnerable Plaque on IVUS with Pressure Wire(Imaging of Vulnerable Plaque,Meet the Expert 8 (ME8) (I),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• CAVI vs. pressure and stiffness gradients in the arterial tree
• Non-Invasive Vascular Function Tests : Their Pathophysiological Background and Clinical Application
• PJ-804 Diagnostic Performance of Contrast Enhanced Cardiac MRI in Patients with Severe Systolic Dysfunction(MRI/MRA-3 (I) PJ142,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• The Influence of the Peripheral Reflection Wave on Left Ventricular Hypertrophy in Patients with Essential Hypertension
• -132-THE SECOND COMPONENT OF LEFT VENTRICULAR SYSTOLIC PRESSURE
• PJ-615 The Evaluation of Salvaged Area at Risk in Acute Myocardial Infarction with Successful Early Revascularization by Cardiovascular Magnetic Resonance(PJ103,CT/MRI (Myocardium) 2 (I),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The
• PJ-348 Microvascular Obstruction with Acute Myocardial Infarction by Late Gadolinium Enhancement with MRI(MRI/MRA(03)(I),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• 3 Detection of acute myocardial infarction with low-b-value diffusion-weighted echo-planar MRI(Symposium 14 (SY-14) (I) New Horizon of CT, MR and PET in Diagnostic Cardiac Imaging,Special Program,The 72nd Annual Scientific Meeting of the Japanese Circulat
• Comparative Study of BMIPP Scintigraphy and Contrast MRI in Detecting the Abnormality in Myocardium of Hypertrophic Cardiomyopathy(X-ray/CT/MRI/DSA 2 (I), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Comparative Study of the Occurrence and Extent of Delayed Contrast Enhancement of MRI between HCM with ASH and APH(X-ray/CT/MRI/DSA 10 (I), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• The New Method for Color Distribution Imaging of Stent with MDCT(X-ray/CT/MRI/DSA 6 (I), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-167 The Relationship Between the Occurrence and extent of Delayed Contrast Enhancement on Contrast MRI and Q wave in Antero-Septal OMI(X-ray/CT/MRI/DSA2 (I) : OJ19)(Oral Presentation (Japanese))
• 7 Evaluation in stent restenosis by MDCT : Dose MDCT play sufficient role for follow up after PCI?(Plenary Session 6 (PL6) (I) : Role of Diagnostic Imaging in the Management of Coronary Artery Disease and Its Cost Effectiveness)(Special Program)
• OJ-243 Medical Cost Effectiveness : Non-invasive Test Guided Versus FFR Guided PCI(Cost-health care system (H),Oral Presentation (Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• OE-403 The 3-years Follow up of Patients with Coronary Artery Disease Treated by Fractional Flow Reserve (FFR) Based Intervention.(Coronary revascularization, PCI(04)(IHD),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circu
• Relationship between Radial and Central Arterial Pulse Wave and Evaluation of Central Aortic Pressure Using the Radial Arterial Pulse Wave
• PJ-517 Fractional Flow Reserve Guided Coronary Stenting in Drug Eluting Stent Era(Coronary revascularization, PCI-18 (IHD) PJ87,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• Importance of Pull-back Intracoronary Pressure Recording After Successful Stenting in Patients with Diffuse Coronary Stenoses(Coronary Revascularization, PTCA/Stent/DCA/Rotablator/New Device 3 (IHD), The 69th Annual Scientific Meeting of the Japanese Circ
• Cut-Off Value of the Ankle-Brachial Pressure Index at Which the Accuracy of Brachial-Ankle Pulse Wave Velocity Measurement is Diminished
• The Age-Related Increase in Arterial Stiffness Is Augmented in Phases According to the Severity of Hypertension
• PJ-614 Brachial-ankle Pulse Wave Velocity is a Marker of the Atherosclerotic Changes in Carotid Artery in Hypertension(Hypertension, Basic and Clinical (H) : PJ103)(Poster Session (Japanese))
• PJ-306 The Cut-off Value of Ankle-brachial Pressure Index to Warrant the Accuracy of Brachial-ankle Pulse Wave Velocity Measurement(Atherosclerosis, Clinical 5 (IHD) : PJ51)(Poster Session (Japanese))
• PJ-291 The Evaluation of the Accuracy of Newly Derived Oscillometric Device to Determine Ankle-Brachial Pressure Index : Its Clinical Application(Atherosclerosis, Clinical 4 (IHD) : PJ49)(Poster Session (Japanese))
• OJ-503 Menopause augments age-related increase in Arterial Stiffness : Its association with the Prevalence of hypertension(Atherosclerosis, Clinical 8 (IHD) : OJ61)(Oral Presentation (Japanese))
• Nomogram of the Relation of Brachial-Ankle Pulse Wave Velocity with Blood Pressure
• Brachial-Ankle Pulse Wave Velocity as a Marker of Atherosclerotic Vascular Damage and Cardiovascular Risk
• Graphical Comparison of Coronary Arterial Culprit Lesions in Acute Myocardial Infarction and Unstable Angina Pectoris
• Correlation Between Thallium-201 Myocardial Perfusion Defects and the Functional Severity of Coronary Artery Stenosis as Assessed by Pressure-Derived Myocardial Fractional Flow Reserve
• Reliability of pressure-derived myocardial fractional flow reserve in assessing the functional severity of coronary-artery stenosis in patients with myocardial infarction
• PE-437 Quantification of Serial Changes in Microvascular Function after Coronary Intervention Using Index of Microcirculatory Resistance(PE073,Myocardial Ischemia-reperfusion (Basic) (IHD),Poster Session (English),The 73rd Annual Scientific Meeting of the
• Close Relationship Between Sympathetic Activation and Coronary Microvascular Dysfunction During Acute Hyperglycemia in Subjects With Atherosclerotic Risk Factors
• PJ-384 Latent Cardiac Dysfunction in Patients with Obstructive Sleep Apnea Syndrome (OSAS)(Echo/Doppler-11 (I) PJ65,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• PE-253 Relation between Stress Hyperglycemia and Left Ventricular Diastolic Function 6 Months after Acute Myocardial Infarction(Echo/Doppler-10 (I) PE43,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation So
• Brachial-Ankle Pulse Wave Velocity is a Simple and Independent Predictor of Prognosis in Patients With Acute Coronary Syndrome
• Stress Hyperglycemia Attenuates Coronary Flow Reserve on Non-Culprit Coronary Artery in Patients with Acute Myocardial Infarction(Echo/Doppler 8 (I), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Application of Pressure-Derived Myocardial Fractional Flow Reserve in Assessing the Functional Severity of Coronary Artery Stenosis in Patients With Diabetes Mellitus
• OJ-037 Acute Hyperglycemia Attenuates Coronary Flow Reserve, but not Peripheral Endothelial Function, via Increased Oxidative Stress Rather Than Sympathetic Activation(Diabetes/Obesity 1 (H) : OJ5)(Oral Presentation (Japanese))
• Coronary Flow-Pressure Relationship Distal to Epicardial Stenosis
• Is It Appropriate for the Determination of Indication of Re-Revascularization by Fractional Flow Reserve?
• Acute Hyperglycemia Attenuates Coronary Flow Reserve in Patients with Glucose Intolerance
• Application of Pressure-Derived Myocardial Fractional Flow Reserve in Assessing the Functional Severity of Coronary-Artery Stenosis in Patients with Diabetes Mellitus
• COMPARISON OF PULSE WAVE VELOCITIES OBTAINED BY NONINVASIVE ABI-form AND DIRECT MEASUREMENT WITH CATHETER MANOMETER : before and after Nitroglycerin
• The Effects of Changes in the Metabolic Syndrome Detection Status on Arterial Stiffening : A Prospective Study
• The Influence of Obstructive Sleep Apnea in the Nocturnal Oxygen Therapy to Heart Failure Patient with Cheyne-Stokes Respiration(Heart Failure, Clinical 5 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Prediction by Neurohumoral Factors of Sinus Rhythm Maintenance after Electrical Cardioversion in Patients with Persistent Atrial Fibrillation(Neurohumoral Factors 1 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Arterial Stiffening as a Possible Risk Factor for Both Atherosclerosis and Diastolic Heart Failure
• Association of blood pressure levels with the effects of alcohol intake on the vasculature in Japanese men
• The Relationships of Cardiovascular Disease Risk Factors to Flow-Mediated Dilatation in Japanese Subjects Free of Cardiovascular Disease
• Brachial-ankle pulse wave velocity as a marker of subclinical organ damage in middle-aged patients with hypertension
• Overweight Body Mass Index Classification Modifies Arterial Stiffening Associated with Weight Gain in Healthy Middle-Aged Japanese Men
• Effects of azelnidipine on the autonomic functions and its influence on arterial stiffness and endothelial functions
• PJ-840 Overweight BMI Classification Modifies Arterial Stiffening Associated with Weight Gain in Healthy Middle-aged Japanese Men(Diabetes / Obesity / Metabolic syndrome(15)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Ci
• Effects of Hydrogen Peroxide on Contraction of Skinned Aorta from Guinea Pigs
• Excessive Alcohol Intake Increases the Risk of Arterial Stiffening in Men with Normal Blood Pressure
• Combination of Natriuretic Peptides and Left Atrial Appendage Function Can Predict Outcome of Electrical Cardioversion of Atrial Fibrillation
• PJ-132 The Effects of Azelnidipine on Autonomic Function and Its Influence on Arterial Stiffness and Endothelial Function(Hypertension, clinical(07)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• Heart Rate Elevation Precedes the Development of Metabolic Syndrome in Japanese Men : A Prospective Study
• OJ-081 Brachial-ankle PWV is a Useful Predictor for the Development of Hypertension in Subjects with Prehypertension(Hypertension, clinical-3 (H) OJ14,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation
• Relationship between Arterial Stiffness and the Risk of Coronary Artery Disease in Subjects with and without Metabolic Syndrome
• Carotid Arterial Plaque Assessed by Ultrasound Examination is a Marker of Cognitive Impairment in Patients with Coronary Artery Disease (Atherosclerosis, Basic 7 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Relation between prognosis and myocardial perfusion imaging from the difference of end-point criterion for exercise stress testing : A sub-analysis of the J-ACCESS study

もっと見る 閉じる

スポンサーリンク