Plant Cell Culture for Production of Paclitaxel and Other Taxanes(PLANT BIOTECHNOLOGY)
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概要
- 論文の詳細を見る
Great advances in cell cultures of Taxus spp. for production of Taxol^TM (generic name: paclitaxel) and other taxanes (taxoids) have been achieved in the past decade. This article reviews the manipulation of inducing factors - elicitors, gas composition, osmotic pressure, and conditioned medium; bioprocessing strategies - combining of inducing techniques, two-phase and two-stage cultivation, semi-continuous and perfusion cultures, and feeding of precursors or sugars; and bioreactors and scale-up. Perspectives on a more rational and efficient process involving metabolic engineering are also discussed.
- 社団法人日本生物工学会の論文
- 2002-12-25
著者
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Zhong J‐j
East China Univ. Sci. And Technol. Shanghai Chn
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ZHONG JIAN-JIANG
State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology
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Zhong J‐j
State Key Laboratory Of Bioreactor Engineering East China University Of Science And Technology
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Zhong Jian-jiang
State Key Lab. Bioreactor Eng. East China University Of Science And Technology
関連論文
- Plant Cell Culture for Production of Paclitaxel and Other Taxanes(PLANT BIOTECHNOLOGY)
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