Investigation of Indoor Air Pollution by Chlorpyrifos : Determination of Chlorpyrifos in Indoor Air and 3,5,6-Trichloro-2-pyridinol in Residents' Urine as an Exposure Index

スポンサーリンク

概要

• 論文の詳細を見る

• Objects: We carried out an investigation to clarify the real state of indoor air pollution by chlorpyrifos (termiticide) and exposure to chlorpyrifos of residents by measuring its urinary metabolite 3,5,6-trichloro-2-pyridinol (TCP) as an exposure index, such as biological monitoring. Methods: The investigation was conducted in 43 individual houses with termiticide application (whether the termiticide was chlorpyrifos is uncertain) and 3 control houses without any termiticide application in Kagawa, Japan. Urine samples were collected from 46 healthy adult residents of the aforementioned houses. Results: Chlorpyrifos in indoor air in the control houses was not detected (ND<1 ng/m^3, n=3), while 41 of 43 houses with termiticide application showed 1-350 ng/m^3. Although the chlorpyrifos concentrations in these 41 houses did not exceeded the indoor air quality guideline of 1000 ng/m^3, but 3 houses were higher than the guideline 100 ng/m^3 for children in Japan. Urinary TCP concentrations of 0.1-7.8 ng/mg-creatinine were detected in 41 residents from the 41 houses where chlorpyrifos had been detected. The chlorpyrifos concentration and the urinary TCP revealed a positive correlation (r=0.5468, p<0.01, n=41). Conclusions: The immediate health hazard from air born chlorpyrifos in the examined houses was negligible, but the findings suggest that it is necessary to monitor chemicals which may contaminate indoor air and to assess the risk of prolonged exposure to such chemicals. The measuring of urinary metabolite TCP of chlorpyrifos via biological monitoring would be useful, allowing comprehensive evaluation of the exposure to chlorpyrifos in indoor air.

• 日本衛生学会の論文

著者

• HIRAO Tomohiro

  Department of Hygiene & Public Health, Faculty of Medicine, Kagawa Medical University

• JITSUNARI Fumihiko

  Department of Hygiene & Public Health, Faculty of Medicine, Kagawa Medical University

• SUNA Shigeru

  Department of Hygiene & Public Health, Faculty of Medicine, Kagawa Medical University

• FUKUNAGA Ichiro

  Department of Hygiene & Public Health, Factulty of Medicine, Kagawa Medical University

• Fukunaga Ichiro

  Department Of Hygiene And Public Health School Of Medicine Kagawa Medical University

• Jitsunari Fumihiko

  Kagawa Univ. Kagawa Jpn

• ASAKAWA Fumiyuki

  Human-Environmental Science Research Laboratory, College of Life Science, Kurashiki University of Sc

• DAI Hong

  Department of Hygiene and Public Health, School of Medicine, Kagawa Medical University

• KARITA Tomonori

  Department of Hygiene and Public Health, School of Medicine, Kagawa Medical University

• Kitamado T

  Department Of Hygiene And Public Health School Of Medicine Kagawa Medical University

• Hirao Tomohiro

  Department Of Public Health And Social Medicine Faculty Of Medicine Kagawa University

関連論文

• Impact of Health Professionals on Health Promotion Activities in Japanese Worksites
• Association between interpersonal relationship among high-school students and mental health
• Tissue Concentrations of Chlordanes in Mice after Long-term Exposures to Technical Grade Chlordane at Indoor Air Levels
• A Method for On-Site Analysis of Urinary Benzene by Means of a Portable Gas-Chromatograph : Short Communication
• Study of Indoor Air Pollution by Permethrin: Determination of Permethrin in Indoor Air and 3-phenoxybenzoic acid in Residents' Urine as an Exposure Index
• Investigation of Indoor Air Pollution by Chlorpyrifos : Determination of Chlorpyrifos in Indoor Air and 3,5,6-Trichloro-2-pyridinol in Residents' Urine as an Exposure Index
• Analysis of Beta3 Adrenergic Receptor Gene Polymorphism Using Noninvasive Samples Obtained at Scheduled Infant Health Checkups
• Study on Biological Monitoring of Fenpropathrin Exposure in Application by Utilizing Urinary 3-Phenoxybenzoic Acid Level
• A Study on Urine Cotinine for the Evaluation of Smoking Cessation
• Tentative Criteria for Assessing Workers Exposure to Toluene by Urinary Toluene Screening
• Changes in Metabolic Syndrome and Its Components with Lifestyle Modification in Japanese Men
• Evaluation of health-related quality of life using EQ-5D in Takamatsu, Japan
• Relation between cigarette smoking and ventilatory threshold in the Japanese
• Evaluation of ventilatory threshold and its relation to exercise habits among Japanese

もっと見る 閉じる

スポンサーリンク