A Consideration of a Mechanism of Augmentation of Peripheral Vascular Resistance in Hypertension : Presence of F-actin Filament in Renal Arterioles and Electrolytes Contents in Arterial Wall in Hypertensive Rat (Goldblatt Type)
スポンサーリンク
概要
- 論文の詳細を見る
It was electronmicroscopically shown that thick and thin filaments similar to myosin aggregates and F-action constituting arterial natural actomyosin were present even in renal arteriolar or capillary endothelium. Amounts of Ca^<2+>, Mg^<2+> and Na^+/K^+ contained in arterial wall appeared to be higher in renovascular hypertensive rats than those in normotensive rats, although amounts of these electrolytes in skeletal muscle were not different between them. Since it has been clarified that free ion concentrations of these electrolytes have influence on the contractile activity of arterial natural actomyosin, the role of these electrolytes in arterial wall for the induction of hypertension was discussed on the basis of a hypothesis that an augmentation in the active contractility of peripheral arterioles may play an etiological role for the essential hypertension.
- 社団法人日本循環器学会の論文
- 1973-12-20
著者
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Shibata Nobuhiko
Center for Adult Diseases
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Oiyama Michiko
The Center For Adult Diseases Osaka Department Of Cardiovascular Diseases
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TANAKA KAZUHIKO
The Center for Adult Disease
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OKAMURA YOSHIMI
The Center for Adult Disease
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Shibata Nobuhiko
Department Of Cardiology The Center For Adult Diseases
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Shibata Nobuhiko
The Center For Adult Disease
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Akagami Hirotaka
Department Of Cardiology The Center For Adult Diseases
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Akagami Hirotaka
The Center For Adult Disease Osaka 1st Dep. Of Medicine
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Okamura Yoshimi
The Center For Adult Diseases Osaka Department Of Cardiovascular Diseases
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Shibata Nobuhiko
Department Of Cardiology The Center For Adult Diseases.
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Akagami Hirotaka
Department Of Cardiology The Center For Adult Diseases.
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