MYOCARDIAL OXYGEN METABOLISM OF THE RIGHT VENTRICLE WITH VOLUME LOADING AND HYPOPERFUSION
スポンサーリンク
概要
- 論文の詳細を見る
A comparison of blood flow and myocardial O_2 consumption (MV^^.O_2) in the right and the left ventricles was made in dogs whose chests had been opened. The effect of volume loading by arterio-venous and arterio-left atrial shunts, and the effect of ventricular hypoperfusion by rapid removal of blood were examined in the presence and absence of the pericardium. Blood flow per unit myocardium was greater in the left anterior descending coronary artery (LAD) than in the right coronary artery (RCA), 75±4.3 vs. 46±2.8 (mean±SE)ml/min per 100g, respectively. Similarly, the myocardial O_2 extraction ratio (EO_2) was 59±2% in the left ventricle and 43±3% in the right ventricle (p<0.001). The MV^^.O_2 was greater for the left than for the right ventricle, 8.0±0.6 vs. 3.5±0.3 ml O_2/min per 100g. volume loadiing to both ventricles by arterio-venous (AV) shunt increased MV^^.O_2 of the right ventricle by augmented EO_2 in addition to a rise in the coronary arterial blood flow. Decrease in aortic pressure by rapid removal of blood increased EO_2 in both ventricles. The increments of EO_2 were greater in the right ventricle than in the left ventricle, 54 vs. 31% (p<0.01). When the pericardium was closed with suture, right and left end-diastolic pressure rose, but EO_2 and coronary blood flow of both ventricles did not change. We conclude that reserve capacity of myocardial O_2 extraction was greater in the right ventricle than in the ventricle.
- 社団法人日本循環器学会の論文
- 1987-05-20
著者
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Haraoka Shoichi
The First Department of Internal Medicine, Okayama University Medical School
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Nagashima Hideo
The First Department of Internal Medicine, Okayama University Medical School
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Haraoka Shoichi
The Central Laboratory of Okayama University Medical School
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TAKEDA KOU
The First Department of Internal Medicine
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NAGAHANA Haruki
The First Department of Internal Medicine Okayama University Medical School
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Haraoka Shoichi
The Department Of Cardiovascular Medicine Okayama University Medical School
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Haraoka Shoichi
Department Of Cardiovascular Medicine Okayama University
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Haraoka Shoichi
The First Department Of Internal Medicine Okayama University Medical School
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Nagashima Hideo
The First Department Of Internal Medicine Okayama University Medical School
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Takeda Kou
The First Department Of Internal Medicine Okayama University Medical School
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Nagashima Hideo
The Ist Dept. Of Intern. Med. Okayama Univ. Med. School
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Nagahana H
First Department Of Internal Medicine Okayama University Medical School
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