Quantitative Analysis of Regional Wall Motion in Dogs in Situ : Characteristics of End-Systolic Pressure-Length Relation : SYMPOSIUM ON MECHANICS OF CONTRACTION AND RELAXATION OF THE ISCHEMIC MYOCARDIUM : 50th Annual Scientific Session of Japanese Circula

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概要

• 論文の詳細を見る

• Regional wall motion was analyzed to deduce the muscle property unique to regional contractile states. End-systolic pressure length relations were evaluated 1) under global changes in a contractile state, 2) under selective intracoronary administration of inotropic agents to produce regional hypo- or hyper-kinesis, and 3) before and after extension of size of the ischemia. Linearity of thee end-systolic pressure-length relation was confirmed in each perturbation; however, the behavior of this relation with regard to changes in the slope and X-axis intercept differed among the three situations. When the contractile state was altered globally by intravenous administration of inotropic agents such as dobutamine and propranolol, the slope of the end-systolic pressure-length relation changed in a manner similar to that seen with the pressure-volume relation or stress-strain relation, with no significant changes in the X-axis intercept. Namely, the level of global cardiac function determined the slope of the end-systolic pressure length relation. When regional hypokinesis was produced pharmacologically by selective intracoronary infusion of lidocaine, the X-axis intercept moved rightward, depending on the degree of regional hypokinesis. Expansion in the size of the ischemic area also shifted the X-axis intercept rightward. The latter two phenomena suggested that the hypokinetic segments were stretched by the surrounding intact myocardium. Accordingly, end-systolic pressure-length relations provide useful information concerning the functional state of regional myocardium. The systolic properties of the regional myocardium rendered hypokinetic have to be quantified so as to include the total geometry of the heart.

• 社団法人日本循環器学会の論文
• 1987-01-20

著者

• UEHARA Yoshio

  University of Tokyo

• Uehara Yoshio

  Second Department Of Medicine University Of Tokyo

• Tomoike H

  Research Institute Of Angiocardiology And Cardiovascular Clinic Faculty Of Medicine Kyushu Universit

• Nakamura Motoomi

  The Research Institute Of Angiocardiology And Cardiovascular Clinic Faculty Of Medicine Kyushu Unive

• Urabe Yoshitoshi

  Research Institute Of Angiocardiology And Cardiovascular Clinic Faculty Of Medicine Kyushu Universit

• Nakamura Motoomi

  Research Institute Of Angiocardiology And Cardiovascular Clinic Faculty Of Medicine Kyushu Universit

• Nakamura Motoomi

  Research Institute Of Angiocardiology And Cardiovascular Clinic And Information Science Laboratory F

• TOMOIKE HITONOBU

  Reserch Institute of Angiocardiology and Cardiovascular Clinic, Faculty of Medicine, Kyushu Universi

• KASEDA SHUNICHI

  Reserch Institute of Angiocardiology and Cardiovascular Clinic, Faculty of Medicine, Kyushu Universi

• URABE YOSHITOSHI

  Reserch Institute of Angiocardiology and Cardiovascular Clinic, Faculty of Medicine, Kyushu Universi

• NAKAMURA MOTOOMI

  Reserch Institute of Angiocardiology and Cardiovascular Clinic, Faculty of Medicine, Kyushu Universi

• Tomoike Hitonobu

  The Research Institute Of Angiocardiology And Cardiovascular Clinic Faculty Of Medicine Kyushu Unive

• Tomoike Hitonobu

  Research Institute Of Angioeardiology And Cardiovascular Clinic Kyushu University

• Tomoike Hitonobu

  Reserch Institute Of Angiocardiology And Cardiovascular Clinic Faculty Of Medicine Kyushu University

• Tonoike Hitonobu

  Research Institute Of Angiocardiology And Cardiovascular Clinic Faculty Of Medicine Kyushu Universit

• Kaseda Shunichi

  Reserch Institute Of Angiocardiology And Cardiovascular Clinic Faculty Of Medicine Kyushu University

• Tomoike Hitonobu

  Research Institute Of Angiocardiology And Cardiovascular Clinic Kyushu University Medical School

• Tomoike Hitonobu

  Research Institute Of Angiocardiology And Cardiovascular Clinic Faculty Of Medicine Kyushu Universit

• Tomoike Hitonobu

  Research Institute Of Angiocardiology And Cardiovascular Clinic Faculty Of Medicine Kyushu Universit

• Nakamura Motoomi

  Research Institute Of Angiocardiology And Cardiovascular Clinic Faculty Of Medicine Kyushu Universit

• Nakamura Motoomi

  Research Institute Of Angiocardiology And Cardiovascular Clinic Faculty Of Medicine Kyushu Universit

• Tomoike Hitonobu

  Research Institute Of Angiocaridology And Cardiovascular Clinic Faculty Of Medicine Kyushu Universit

• Urabe Yoshitoshi

  Reserch Institute Of Angiocardiology And Cardiovascular Clinic Faculty Of Medicine Kyushu University

• Tomoike Hitonobu

  Research Institute Of Angiocardiology And Cardiovascular Clinic Faculty Of Medicine Kyushu Universit

• Uehara Yoshio

  The Second Department Of Medicine University Of Tokyo

• NAKAMURA Motoomi

  Reserch Instit, of Angiocardiology, Kyushu University Med. Sch., FUKUOKA

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