HYPERCOAGULABILITY IN PATIENTS WITH MITRAL STENOSIS : From the Viewpoint of the Behavior Plasma Antithrombin III and Alpha2-plasmin Inhibitor
スポンサーリンク
概要
- 論文の詳細を見る
The concentration of plasma antithrombin III (AT III) and the biological activity of plasma alpha2-plasmin inhibitor (α_2 -PI) were measured in cases of mitral stenosis (MS) and rheumatic heart disease (RHD) without MS. Cases of MS showed the findings of the low levels of plasma AT III and and normal or a little higher levels of plasma α_2 -PI, that was not recognized in RHD without MS. This finding was interpreted to be hypercoagulable because of the acceleration of coagulation and of little or slight retardation of fibrinolysis. Besides, the influence of atrial fibrillation and chronic congestive heart failure on hypercoagulability in cases of MS was detected clearly, but the influence of them in cases of non-RHD was obscure. As the results, the severer the degree of MS, the clearer the hypercoagulable state. Therefore, the prethrombotic state existed in cases of MS, combined with blood flow disturbance due to atrial fibrillation or chronic congestive heart failure, endocardial damage resulted from rheumatic fever in an early stage and hypercoagulable state mentioned above in the present study. There was no significant difference between cases with and without thrombi in the degree of hypercoagulability in subjects with MS shown in the present work. It was concluded that the consumption of AT III caused the low levels of it in cases of MS, and that the low production of AT III in the liver rather than consumption caused the low levels of it in cases of non-RHD.
- 社団法人日本循環器学会の論文
- 1980-12-20
著者
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Hashimoto Shuji
The 2nd Dep. Of Intern. Med. Kagoshima Univ.
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NAKAMURA Kazuhiko
2nd Division of Cardiovascular Medicine, National Hospital Organization Kagoshima Medical Center
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Nakamura Kazuhiko
Second Department Of Cardiology Kagoshima Medical Center National Hospital Organization
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Takaoka Shigeru
The Second Department of Internal Medicine, Kagoshima University
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Sanada Jun-ichi
2nd Department of Internal Medicine Kagoshima University School of Medicine
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Kuroiwa Nobuchika
2nd Department of Internal Medicine Kagoshima University School of Medicine
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Hashimoto Shuji
2nd Department of Internal Medicine Kagoshima University School of Medicine
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Tabuchi Hiromi
The 2nd Dept. of Int. Med. Kagoshima University School of Medicine
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Kataoka Hajime
The 2nd Dept. of Int. Med. Kagoshima University School of Medicine
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Minami Yukihiro
The Second Department of Internal Medicine, Faculty of Medicine, Kagoshima University
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FUKUDA Yohichiroh
The Second Department of Internal Medicine, Kagoshima University School of Medicine
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Takaoka Shigeru
2nd department of Internal medicine, Kagoshima university, Kagoshima
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Kataoka Hajime
2nd department of Internal medicine, Kagoshima university, Kagoshima
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Miyahara Kenkichi
2nd department of Internal medicine, Kagoshima university, Kagoshima
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Fukuda Yohichiroh
2nd Department of Internal Medicine, School of Medicine Kagoshima University, Kagoshima
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Kuroiwa Yoshifumi
2nd Department of Internal Medicine, School of Medicine Kagoshima University, Kagoshima
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Ohshige Tamao
2nd Department of Internal Medicine, School of Medicine Kagoshima University, Kagoshima
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FURUKAWA SHIGEHARU
The Second Department of Internal Medicine, Kagoshima University School of Medicine
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Okumiya Kazuya
Department of Internal Medicine 2, School of Medicine, Kagoshima University
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OKUMIYA KAZUYA
2nd Department of Internal Medicine, School of Medicine, Kagoshima University
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TABUCHI HIROMI
2nd Department of Internal Medicine, School of Medicine, Kagoshima University
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SANADA JUNICHI
2nd Department of Internal Medicine, School of Medicine, Kagoshima University
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MINAMI YUKIHIRO
2nd Department of Internal Medicine, School of Medicine, Kagoshima University
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FURUKAWA SHIGEHARU
2nd Department of Internal Medicine, School of Medicine, Kagoshima University
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Nakamura Kazuhiko
The 2nd Dep. Of Intern. Med. Kagoshima Univ.
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Tabuchi Hiromi
The Second Department Of Internal Medicine Kagoshima University
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Tachibana Hiroki
2nd Division Of Cardiology National Minami-kyushu Chuo Hospital
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Miyahara Kenkichi
Department Of Cardiology And Cardiovascular Surgery Shinkyo Hospital
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Furukawa Shigeharu
The Second Department Of Internal Medicine Kagoshima University School Of Medicine
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Sanada Junichi
2nd Department Of Internal Medicine Kagoshima University School Of Medicine
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Okumiya Kazuya
Department Of Internal Medicine 2 School Of Medicine Kagoshima University
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Kurokawa Yoshifumi
The Second Department Of Internal Medicine Kagoshima University School Of Medicine
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Fukuda Yohichiroh
The Second Department Of Internal Medicine Kagoshima University School Of Medicine
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Ohshige Tamao
The Second Department Of Internal Medicine Faculty Of Medicine Kagoshima University
-
Minami Yukihiro
The Second Department Of Internal Medicine Faculty Of Medicine Kagoshima University
-
Hashimoto Shuji
The 2nd Dept.of Intern.ned. Kagoshima Univ.school Of Med
-
Takaoka Shigeru
The Second Department Of Internal Medicine Kagoshima University
-
Nakamura Kazuhiko
2nd Department Of Internal Medicine Kagoshima University School Of Medicine
-
Tachibana Hiroki
The 2nd Dep. Of Intern. Med. Kagoshima Univ.
-
Kataoka Hajime
Div. Of Cardiology And Dept. Of Nuclear Med. Tokyo Metropolitan Geriatric Hospital
-
Hashimoto Shuji
The Second Department Of Internal Medicine Faculty Of Medicine Kagoshima University
-
Miyahara Kenkichi
Department Of Cardiology Shinkyo Hospital
-
Miyahara Kenkichi
The Second Dept. Of Intern. Med. Kagoshima Univ. School Of Med.
-
Nakamura Kazuhiko
2nd Division Of Cardiovascular Medicine National Hospital Organization Kagoshima Medical Center
-
Nakamura Kazuhiko
Division Of 2nd Cardiology National Hospital Organization Kagoshima Medical Center
-
Takaoka Shigeru
Div. Of Cardiology And Dept. Of Nuclear Med. Tokyo Metropolitan Geriatric Hospital
-
Tabuchi Hiromi
The Second Department Of Internal Medicine Faculty Of Medicine Kagoshima University
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