EFFECTS OF PULMONARY HEMODYNAMICS ON LUNG FUNCTION IN ADLU PATIENTS WITH ATRIAL SEPTAL DEFECT
スポンサーリンク
概要
- 論文の詳細を見る
To clarify the relationship of pulmonary function with differing severity of atrial septal defect (ASD) and to assess the effects of pulmonary hemodynamics on these functions, we classified 101 patients with adult ASD by their pulmonary arterial mean pressure (PAm) and pulmonary blood flow (Qp), and compared details of pulmonary functions between pairs of groups. Classification was by drawing lines at the PAm of 20 mmHg and the Qp of 10 L/min. Group I was the low pressure-low flow group, Group II the low pressure-high flow group, Group III the high pressure-low flow group, and Group IV the high pressure-high flow group. Vital capacity as the percentage of predicted (%VC) was low in Group III and IV. There were no significant differences in the ratio of forced expiratory volume in one second to forced vital capacity (FEVl%), flow at 25% forced vital capacity and colsing volume as the percentage of predicted (%V25, %CV/VC) between each group. Both maximum midexpiratory flow rate and flow rate at 50% forced vital capacity as the percentage of predicted (%MMEF, %V50) in Group III with the most severe ASD, were significantly low. Pulmonary diffusing capacities for carbon monoxide as the percentage of predicted (%DLco) exceeded 100% in all groups, and tended to decrease with increases of PAm without relation to Qp. Pulmonary dysfunctions in adult ASD were mainly due to restrictive changes accompanied by obstructive change in proportion to the decrease of VC. Peripheral airway obstructions are mild in ASD and these might be caused by lower pressure of left atrium and no existence of pulmonary venous congestion in ASD, even in the most severe group.
- 社団法人日本循環器学会の論文
- 1985-09-20
著者
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Nakanishi Norifumi
Division Of Cardiology Department Of Medicine National Cardiovascular Center
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Nakanishi Norifumi
Department Of Cardiovascular Medicine National Cardiovascular Center
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Nakanishi Norifumi
National Cardiovascular Center
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Okubo Shumpei
Division of Cardiology, Department of Medicine, National Cardiovascular Center
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Yoshioka Takao
National Cardiovascular Center Hospital
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NAITO MASAHIRO
Cardiopulmonary Division, Department of Medicine, National Cardiovascular Center
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NAITO MASAHIRO
Department of Internal Medicine, National Cardiovascular Center Hospital
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OKUBO SHUMPEI
Department of Internal Medicine, National Cardiovascular Center Hospital
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KUNIEDA TAKEYOSHI
Department of Internal Medicine, National Cardiovascular Center Hospital
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FUKUNAGA YASUO
Department of Internal Medicine
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Yoshioka Takao
Division Of Cardiology Department Of Medicine National Cardiovascular Center
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Kunieda Takeyoshi
化学療法研究所附属病院 循環器内科
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Kunieda Takeyoshi
Division Of Cardiology Department Of Medicine National Cardiovascular Center
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Kunieda Takeyoshi
国立循環器病センター研究所
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Ookubo Shunpei
Division Of Cardiology Department Of Medicine National Cardiovascular Center
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Okubo Shumpei
国立循環器病センター研究所
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Okubo Shumpei
Departments Of Cardiology And Cardiovascular Dynamics National Cardiovascular Center
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Naito Masahiro
Cardiopulmonary Division Department Of Medicine National Cardiovascular Center
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Naito Masahiro
国立循環器病センター研究所
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Naito Masahiro
Department Of Physics Faculty Of Science University
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Naito Masahiro
Department Of Internal Medicine National Cardiovascular Center
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Kuriyama Takayuki
Chiba University Graduate Schoolof Medicine
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Nakanishi Norifumi
Department Of Cardiology Jichi Medical School
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Nakanishi Norifumi
Cardiac Division Department Of Internal Medicine National Cardiovascular Center
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Yoshioka Takao
国立循環器病センター研究所
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Okubo Shumpei
Division Of Cardiology Department Of Medicine National Cardiovascular Center
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Kunieda Takeyoshi
Cardiac Division Department Of Internal Medicine National Cardiovascular Center
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Kunieda Takeyoshi
Department Of Cardiovascular Medicine Kaken Hospital Clinical Medicine Research Center International
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Yoshioka Takao
Cardiac Division Department Of Internal Medicine National Cardiovascular Center
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Yoshioka Takao
National Cardiovascular Center
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