Pathophysiologic Features of Pulmonary Thromboembolism in Man : SYMPOSIUM ON CLINICAL ASPECTS OF THROMBOEMBOLISM

概要

論文の詳細を見る
The current study was done to clarify the recent trend of clinical pulmonary thromboembolism (PTE) in Japan. The time has long passed since thromboembolic diseases of the lung were rare in our country. We have experienced, however, tweny-four clinically manifested patients with PTE during the past two years. Although a number of symptoms and findings have been reported to facilitate the diagnosis, they were for the most part nonspecific and therefore nondiagnostic. Combined perfusion and ventilation scans showing a perfusion defect with normal ventilation were reported to be useful for diagnosis of PTE, but a special attention should be paid to the fact that a massive perfusion defect was accompanied by decreased ventilation of the affected lung. From a pathophysiologic study, an exertional dyspnea associated with increased _< A-a > DO_2 and also increased _< a-ET > DCO_2 in patients without apparent pulmonary consolidation on their chest roentgenogram was strongly suggestive of PTE. _< A-a > DO_2 and _< a-ET > DCO_2 were shown to be variables independent to each other. _< a-ET > DCO_2 was valuable for clinical diagnosis with direct evidence of high V_A/Q units resulting from occluded pulmonary arteries. On the other hand, _< A-a > DO_2 which was once elevated in the acute stage of PTE was decreased according to the recovery with a close liner correlation to the actual perfusion defect and was a sensitive indicator suggestive of resolved emboli. _< A-a > DO_2 was considered to provide measures of the active severity of PTE unlike _< a-ET > DCO_2.
社団法人日本循環器学会の論文
1984-01-20

Pathophysiologic Features of Pulmonary Thromboembolism in Man : SYMPOSIUM ON CLINICAL ASPECTS OF THROMBOEMBOLISM

スポンサーリンク

概要

著者

関連論文

スポンサーリンク