Doppler Echocardiography-Derived Index of Myocardial Performance (TEI Index) : Comparison With Brain Natriuretic Peptide Levels in Various Heart Diseases
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概要
- 論文の詳細を見る
Plasma brain natriuretic peptide (BNP) has diagnostic and prognostic value in heart failure. Cardiac dysfunction varies from systolic or diastolic dysfunction alone to the combination of both. In the present study, Doppler echocardiographic parameters, including the Doppler echocardiography-derived index (TEI index), were compared with plasma BNP levels in 74 patients with various heart diseases. Blood sampling was performed before an echocardiographic examination was conducted. The TEI index was defined as the summation of isovolumic contraction and relaxation time divided by ejection time. In patients with left ventricular (LV) systolic dysfunction (ejection fraction <50%), the TEI index and BNP were increased significantly compared with patients with normal LV systolic function (p<0.05). Patients with a TEI index ≥0.45 showed significantly increased BNP levels compared with patients with a TEI index <0.45, irrespective of LV systolic function (241.4±451.2 vs 65.9±81.8 pg/ml;p<0.05). The TEI index was significantly higher in patients with a BNP ≥73 pg/ml than in patients with BNP <73 pg/ml (0.57±0.24 vs 0.46±0.17; p<0.05). Other echocardiographic parameters did not correlate significantly with levels of plasma BNP. Of the echocardiographic parameters, a simple Doppler index (TEI index) that combines systolic and diastolic function can detect LV dysfunction in patients with high levels of plasma BNP in various heart diseases.
- 社団法人日本循環器学会の論文
- 2001-06-20
著者
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Tamita Kouichi
神戸市立中央市民病院
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Tanabe Kazuaki
Division Of Cardiology Shimane University Faculty Of Medicine
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Tanabe Kazuaki
神戸市立医療センター中央市民病院 循環器内科
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Tanabe Kazuaki
Division Of Cardiology Kobe General Hospital
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Yoshitomi Hiroyuki
Division Of Cardiovascular Medicine Shimane University Faculty Of Medicine
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Ono Miwa
Fourth Department of Internal Medicine, Shimane Medical University
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Asanuma Toshihiko
Fourth Department of Internal Medicine, Shimane Medical University
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Yoshitomi Hiroyuki
Fourth Department of Internal Medicine, Shimane Medical University
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Shimizu Hiromi
Fourth Department of Internal Medicine, Shimane Medical University
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Ohta Yoko
Fourth Department of Internal Medicine, Shimane Medical University
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Shimada Toshio
Fourth Department of Internal Medicine, Shimane Medical University
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Shimada Toshio
Division Of Cardiobascular Medicine Shimane University Faculty Of Medicine
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Ono Miwa
The 4th Department Of Internal Medicine Shimane Medical University
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Ohta Yoko
Division Of Cardiovascular Medicine Department Of Internal Medicine Shimane University Medical Schoo
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Shimizu Hiromi
Division Of Cardiovascular Medicine Department Of Internal Medicine Shimane University Medical Schoo
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Asanuma Toshihiko
Fourth Department Of Internal Medicine Shimane Medical University
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Yoshitomi Hiroyuki
The 2nd Department Of Internal Medicine Matsue City Hospital
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Shimada Toshio
Fourth Department Of Internal Medicine Shimane Medical University
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Yoshitomi Hiroyuki
Division Of Cardiology Shimane University Faculty Of Medicine
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