Angiocardiographic Study of Coarctation of the Aorta : Morphology and Morphogenesis : SYMPOSIUM ON CLINICAL PROBLEMS IN AORTIC DISEASES
スポンサーリンク
概要
- 論文の詳細を見る
Angiocardiographic morphology and associated cardiac anomalies of the coarctation of the aorta (COA) were analysed in the light of recently advanced theory of its morphogenesis. Analysis of 154 clinical cases of COA revealed the presence of associated cardiac anomalies which could obstruct fetal blood flow to the ascending aorta in many cases. Systolic left ventricular outflow tract was significantly narrow in cases of ventricular septal defect (VSD) associated with COA in comparison with the isolated VSD (p < 0.01). Good quality aortograms obtained from 41 cases of COA were analysed. Ages ranged from one month to 20 years and major cardiac anomalies were associated in 25 cases. Age-matched 37 cases were studied as the controls. In COA, the isthmus was narrower than the controls in 88% of the cases, and in the remaining it was low in the normal range. Severely hypoplastic isthmus in early infancy became the adult type after 5 years in one of the 4 cases which had repeated aortography. Localized stenosis at the distal end of isthmus was present in 89%, and absent in 11% (4 cases). In these 4, isthmal narrowing was associated with major intracardiac anomalies, large patent ductus arteriosus (PDA) and pulmonary hypertension (PH). The anterior ostium to the descending aorta was obstructed by constricted ductus arteriosus in some infants with COA. These angiographic findings are compatible with the following working hypothesis: ischemic hypoplasia results from prenatal decrease of blood flow to the ascending aorta, and localized stenosis is related to abnormal distribution of the ductal tissue to the descending aorta and post-natal constriction of the ductus arteriosus. In 3 infants COA was associated with persistent fifth aortic arch.
- 社団法人日本循環器学会の論文
- 1982-02-20
著者
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Momma Kazuo
Department Of Pediatric Cardiology The Heart Institute Tokyo Women's Med. Coll.
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Ando Masahiko
Department Of Pediatric Cardiology The Heart Institute Of Japan Tokyo Women's Medical College
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TAKAO ATSUYOSHI
Depertment of Pediatric Cardiology, The Heart Institute of Japan, Tokyo Women's Medical College
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MOMMA KAZUO
Depertment of Pediatric Cardiology, The Heart Institute of Japan, Tokyo Women's Medical College
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Ando Masahoko
Dept. Of Pediatric Cardiology The Heart Institute Of Japan Tokyo Women's Medical College
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Momma Kazuo
The Heart Institute Of Japan Tokyo Women's Medical College
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Momma Kazuo
Department Of Pediatric Cardiology And Research Division Heart Institute Of Japan Tokyo Women's
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ANDO MASAHIKO
Depertment of Pediatric Cardiology, The Heart Institute, Tokyo Women's Medical College
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Ando Masahiko
Dept. Of Pediatric Cardiology The Heart Institute Of Japan Tokyo Women's Medical College
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Momma Kazuo
Section Of Pediatrics And Surgery Heart Institute Tokyo Women's Medical College
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Ando Michiko
Dept. Of Pediatric Cardiology The Heart Institute Of Japan Tokyo Women's Medical College
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Mori Kazuhiro
The Heart Institute Japan Tokyo Women's Medical College
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Takao Atuyoshi
Pediatric Cardiology Heart Institute Tokyo Women's Medical College
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Momma Kazuo
Depertment Of Pediatric Cardiology The Heart Institute Of Japan Tokyo Women's Medical College
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Takao Atsuyoshi
Depertment Of Pediatric Cardiology The Heart Institute Of Japan Tokyo Women's Medical College
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Ando Michiko
The Heart Institute Of Japan Tokyo Women's Medical College
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Momma Kazuo
Division Of Pediatrics And Surgery Heart Institute Tokyo Women's Medical College.
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