635 模擬関節液に関する研究

概要

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In simulation studies concerning wear of ultra-high molecular weight polyethylene (UHMWPE) used in joint prostheses, representative themes seem to be the lubricating liquid used in testing and the sliding direction of UHMWPE. Thee types of research are necessary in order to equalize results in vitro with results in vivo. The important point to note is that bovine serum has been used extensively as a lubricating liquid in these researches. The bovine serum is a good lubricating liquid, but considerable variation in the quality produces scattering result in wear of the UHMWPE. This report presents a simulated synovial fluid that we can make in laboratory settings. The liquid was a water-based liquid and contained the principal constituents of synovial fluid. Wear tests of UHMEWPE showed that boundary lubricating performance of the simulated fluid was equal to that of bovine serum.
一般社団法人日本機械学会の論文
2003-08-05