6.アレルギー性反応におけるキニン系の意義 : アレルギー反応に対するブラディキニンの増強作用(第4回プラスマキニン研究会)

概要

論文の詳細を見る
The effect of bradykinin to allergic reaction was examined. As the allergie reaction, Arthus reaction in actively sensitized rabbits with egg-albumin, PCA (passive cutaneous anaphylaxis) in guinea pigs with egg-albumin and anti-rabbit egg albumin system, Schwartzman phenomenon (Schwartzman filtrate isolated from E. coli filtrate) in robbits and Thomas reaction in rabbits were tested. Synthesized bradykinin was usually intravenously administered within 5 minutes after the challenging injection except in the cases of Arthus phenomenon 2 hours after the challenging injection. The results show that the administretion of bradykinin potentiate the allergic or allergy-like reaction such as Arthus reaction, PCA, Schwartzman phenomenon and Thomas reaction. These results may suggest the role of bradykinin in allergic reaction.
日本アレルギー学会の論文
1970-08-30