結核性空洞の形成阻止に関する実験的研究特に抗アレルギー剤投与の量的影響について

概要

論文の詳細を見る
Yamamura et al. have previously reported that an antigen-antibody reaction in tuberculosis plays an important role in cavitation of lungs. According to these findings, it was attempted to prevent the experimental formation of tuberculous cavities in rabbit lungs by the daily injections of anti-allergic drugs. Various doses of cortisone acetate, "Strong Neo-Minophagen C"and"Glycyron"were injected to the experimental animals subcutaneously, which received the treatment to produce tuberculous cavities by Yamamura's method. The animals were sacrificed for pathological examinations 50 and 80 days after pulmonary injections. Productive changes were significantly pronounced in the lungs of the animals injected"Glycyron"1 mg/kg and cortisone 2 mg/kg, while exudative as well as caseous changes were remarkably found in the other animals.
日本アレルギー学会の論文
1960-09-01