動脈内軸対称狭さく部の成長過程のモデル化とシミュレーション

概要

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There are several hypotheses as to why stenosis appears in an artery. However, there is no accepted theory as yet. In this study, axisy mmetric stenosis growth in an artery is modeled based on three hypotheses; (1) high wall shear stress theory (2) low wall shear stress theory (3) oscillatory shear index theory. In each hypothesis, stenosis growth is simulated numerically. Flow is assumed to be periodic, incompressible and axisymmetric. Non-Newtonian viscosity of blood and movement of arterial wall are considered. Flow pattern, concentration pattern and distribution of mass flux on the wall are computed. By using these results, stenosis growth process is obtained. It is found that the stenosis growth process based on the high wall shear stress theory is consistent with the clinical case. However, stenosis does not grow so much in the case of the low wall shear stress theory and the oscillatory shear index theory.
一般社団法人日本機械学会の論文
1999-09-25