Follow-up Studies of Breast Cancer Incidence among Atomic Bomb Survivors : II. BIOLOGICAL EFFECTS

概要

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Although breast cancer rates among Japanese women are normally very low compared to other countries, the excess risk associated with exposure to ionizing radiation, as observed in the Life Span Study Sample (LSS) sample of the Radiation Effects Research Foundation (RERE), Hiroshima and Nagasaki, is fully as high as that seen in medically-irradiated Westem populations. This combination of a high radiation-related excess and a relatively low baseline level of risk means that the LSS cohort is especially informative about radiation-induced breast cancer. In this paper we review the results of published studies of breast cancer incidence and mortality among A-bomb survivors, their relationship to findings from studies of other irradiated populations, and their possible implications for radiation-induced cancer in general. We conclude with an overview of current studies, which extend beyond the investigation of risk as a function of radiation dose.
日本放射線影響学会の論文