A New Index of Risks for Lethal Diseases by lonizing Radiation
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概要
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Estimates of the somatic risk of radiation exposure have mainly been based on the incidence of fatal cancers. An improvement on the estimates of the risk will be made by taking mean ages at deaths into consideration in addition to the incidence of cancer. The authors report on an index of contribution of each cause of death to life shortening. The index is the sum of three terms. The first term indicates a contribution of change in incidence and the second term indicates that of changes in mean age at death from the cause of death in question. The last term is an interaction term of the two factors mentioned above. If a radiation exposure increases incidence of a cause of death and shortens the mean age at death from the cause of death, the index gives a large positive value. On the other hand, an increase in incidence of a late occurring cause of death will bring about a small positive or sometimes negative value for the index. The index proposed here will be promising in estimating risks by ionizing radiation. Estimates by International Commission on Radiological Protection on the somatic risk of radiation exposure have mainly been based on the incidence of fatal cancers. However, the Commission states in Publication 27 that "A third defect in the use of fatality rates alone is that the length of life lost by the deaths is more important than the fact of death alone". The authors also think that a risk of cancer would better be measured by its contribution to life shortening. Age specific mortalities of A-bomb survivors at Hiroshima and Nagasaki have suggested that causes of death except malignant neoplasms may not induce life shortening.
- 日本放射線影響学会の論文
著者
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- A New Index of Risks for Lethal Diseases by lonizing Radiation
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