Chromosome Aberratlons in Somatlc Cells

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概要

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• Evidence concerning cytogenetic effects of A-bomb irradiations on the somatic cells of survivors of Hiroshima and Nagasaki is reviewed. It has been demonstrated that (1) radiation-induced chromosome aberrations have persisted in the circulating lymphocytes as well as in the bone marrow cells of survivors more than two decades after radiation exposure, and (2) that the chromosome-aberration frequency is in general proportional to the dose received. The relation, if any, between the occurrence of induced structural rearrangements of chromosomes and the health status of the survivors is as yet unknown, and the need for further and continued evaluation for possible associations between them is stressed. It has been well established that ionizing radiations induce breakage and rearrangement of the chromosomes in somatic as well as germ cells of plants and animals. The frequency of these abnormalities have been demonstrated to be proportional to the dose administered.

• 日本放射線影響学会の論文

著者

• 阿波 章夫

  放射線影響研

関連論文

• In Vitro Life Span and UV Sensitivity in Cells Obtained from a Multimalformed Premature Human Fetus
• Comparison of Type and Frequency of Chromosome Aberrations by Conventional and G-staining Methods in Hiroshima Atomic Bomb Survivors
• Genetic Effects : Cytogenetis Study
• Chromosome Aberratlons in Somatlc Cells
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• 細胞遺伝学的立場からみた原爆後障害の問題 (第17回原子爆弾後障害研究会講演集) -- (遺伝学的立場からみた原爆後障害の問題)

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