子宮外に平滑筋腫を認め,性ステロイドホルモンに対して異なる影響が示唆された2症例

概要

論文の詳細を見る
Endocrine dependency of benign metastasizing leiomyoma (BML) has been postulated. We report two cases of BML that were treated with manipulation of gonadal steroids. Patient 1:A 39-year-old woman was diagnosed with BML on open lung biopsy for dyspnea. The patient conceived after danazol and chemotherapy. The symptoms and the size of lung lesions spontaneously diminished after two cesarean sections. Patient 2:A 41-year-old woman was diagnosed with BML on thoracoscopic lung biopsy. Recurrent retroperitoneal metastasis was discovered after GnRH-agonist therapy. The patient underwent TAH-BSO and dissection of a retroperitoneal lesion. The pulmonary BML has been unchanged for two years since the operation. These cases underscore the hypothesis of hormonal dependency of BML and the effects of gonadal steroids for BML may be different.
社団法人日本産科婦人科学会の論文
2002-06-01