母親と Basedow 病の経過中の娘にみられた甲状腺乳頭癌の家族内発生

概要

論文の詳細を見る
Familial occurrence of papillary thyroid carcinoma, one of the patients was in childhood, is extremely rare in Japan. Two cases with the carcinoma of the thyroid, occurring in a mother and her daughter with Graves' disease, were described. Case 1 : A 14-year-old girl, who had previously been treated for Graves' disease with propyl-thyouracil for five years, was admitted in March 1987 with left cervical tumor. Sub-total thyroidectomy was carried out, and histological findings showed papillary carcinoma of the thyroid and hyperthyroidism. Case 2 : (mother of Case l) A 22-year-old female with left cervical tumor underwent left hemithyroidectomy in July 1970. Histological diagnosis showed papillary carcinoma of the thyroid. We are inclined to suppose that in Case 1 Graves' disease and some familial factor, probably genetic, play an important role in carcinogenes of the developing thyroid gland. So, it is important to pay careful attention to a family history of thyroid carcinoma and concurrent car cinoma in treating Graves' disease.
日本小児外科学会の論文
1989-02-20