レーザー組織血流計及び双方向性超音波血流計による位置負荷 : 末梢循環応答の分析

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The effects of the gravitational potential energy change (GPEC) and the thermal stress on finger microvascular responses were studied by laser Doppler and ultrasonic Doppler flowmetry. Seven healthy male subjects, aged 21 to 31 yrs, participated in the experiment after giving their informed consent. The hand was moved upward(about 60 cm)or downward(about 55cm)from the heart level to change the vascular transmural pressure of the finger (GPEC). Sensors of laser Doppler and ultrasonic Doppler flowmeters were attached to the lateral side of the first finger and the skin surface over the radial artery, respectively. Experimental room temperature was maintained at 24℃. Laser Doppler flow (LDF) was decreased at an elevated and lowered arm position. The pulsatile component of LDF, evaluated by the difference between systolic and diastolic LDF, increased when the arm was elevated, but it showed no significant changes when the arm was lowered. Mean blood velocity (MBV) and diastolic blood velocity (DBV) of radial artery decreased when the arm was elevated, whereas the pulsatile blood velocity (PBV), evaluated by the difference between systolic blood velocity (SBV) and DBV, were increased. At the lowered arm position, SBV and PBV decreased significantly, but DBV showed no significant changes. The thermal stress (43, 10min) increased the PBV when the arm was elevated, but the PBV diminished the decreasing rate when the arm was lowered. These results suggest that the measurements used may be useful for the analysis of arteriolar compliance and microvascular response to the change of transmural pressure produced by the gravitational potential energy change.
日本体力医学会の論文
1990-04-01

レーザー組織血流計及び双方向性超音波血流計による位置負荷 : 末梢循環応答の分析

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