TMSとH-reflexによるヒトの随意運動制御メカニズムの解析

概要

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There has been increased interest in the motor control ability of the adult human nervous system to reorganize and adapt to environmental changes throughout life. In the last decade, motor evoked potentials (MEPs) in response to transcranial magnetic stimulation (TMS) has been used increasingly as a tool to investigate the above-mentioned neural mechanisms in the intact human cortex. Because the spatial accuracy of the technique is limited, it is considered to be merely a useful indicator at the cortical level, similar to H-reflexes at the spinal level. Based on recent data for these two useful parameters, I review the differences in neurophysiological background between them. In the first section, I review the neural background of H-reflexes at the spinal level, and in the second section, that of MEPs at the cortical level. Finally, using these parameters, I show experimental evidence for neural mechanisms of human motor control.
2004-07-10