造影剤による腎機能低下の予防を目的としたアセチルシステインゼリーの調製と評価

概要

論文の詳細を見る
Acetylcysteine is used for the prevention of radiocontrast-induced reductions in renal function. However, as an oral solution, acetylcysteine has an unpleasant taste and smell, which can cause discomfort to patients. To solve this problem, we prepared an oral jelly of acetylcysteine consisting of acetylcysteine, gelatin, flavoring agent and purified water. The unpleasant taste and smell of acetylcysteine were greatly reduced through the use of flavoring agents like apple. We expect our acetylcysteine jelly to be a highly effective preparation for the prevention of radiocontrast-induced reductions in renal function.
日本医療薬学会の論文
2005-05-10