S23 Transgenic Mice as Systems for Analyses of Biological Functions

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概要

• 論文の詳細を見る

• Recent advances in biotechnologies have made it possible to manipulate mammalian embryos. This technology in combination with the recombinant DNA technology provides embryos with new and purpose oriented genetic information. Subsequent embryo transfer to the pseudopregnant females also makes these manipulated embryos develop to term as transgenic animals. Transgenes integrated in the transgenic animals are usually transmitted to their off-spring according to the Mendel's Law. Therefore, once we obtained a particular transgenic animal, we could rear them as a strain non-existent in nature. In this report, methods of producing transgenic mouse and a few examples which were applied to the analyses of biological functions are mentioned .

• 日本トキシコロジー学会の論文
• 1988-11-25

著者

• Katsuki Motoya

  Department Of Dna Biology School Of Medicine Tokai University:central Institute For Experimental Ani

• Katsuki Motoya

  Department Of Dna Biol. Embryo Engeneering Institute Of Medical Science University Of Tokyo

関連論文

• Rare Activation of the Human c-Ha-ras Transgene of Mice in Hemangioendothelial Sarcomas and Liver Tumors Induced by Glu-P-1
• Ca^-Sensitization of Contraction in the h1 Calponin-Deficient Smooth Muscle
• Anomalies in Transgenic Mice Carrying the Human Interleukin-2 Gene
• Simple and Efficient Vitrification Procedure for Cryopreservation of Mouse Embryos
• A Mouse Cdc7/Homologue of H37 Complex : Targeted deletion of the murine Cdc7 gene cause early embryomic lethality.
• S23 Transgenic Mice as Systems for Analyses of Biological Functions
• Generation of Transgenic Mice with Human Renin and Angiotensinogen Genes

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