TWENTY-EIGHT WEEK TOXICITY STUDY OF PERLITE POWDER IN MICE
スポンサーリンク
概要
- 論文の詳細を見る
Groups of 21 male and 21 female mice were given diets containing 20%, 10%, 1% or 0%(control) perlite for 28 weeks. Appearance, behavior, mortality, and food consumption of mice of treated groups were not affected during the experimental period. Males of the 20% and 10% groups did experience slightly reduced growth rate. No significant drug-related changes were found in urinalysis, hematology, serum chemistry, and organ weight. No differences were found between control and treated groups in autopsy and histopathological findings. Therefore, the maximum no-effect level is considered to be 1% in the diet which developed no toxic changes in any items examined in mice treated orally with perlite for 28 weeks.
- 日本トキシコロジー学会の論文
- 1985-05-25
著者
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SAKAI TAKEO
Department of Pediatrics, Tohoku University School of Medicine
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Sakai T
Yamanouchi Pharmaceutical Co. Ltd.
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NAGAO Soshichi
Department of Veterinary Hygiene, College of Agriculture and Veterinary Medicine, Nihon University
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Nagao Soshichi
Department Of Veterinary Hygiene College Of Agriculture And Veterinary Medicine Nihon University
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Sakai Takeo
Department Of Pediatrics Tohoku University School Of Medicine
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Sakai Takeo
Department Of Veterinary Hygiene College Of Agriculture And Veterinary Medicine Nihon University
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