トリアゾラム錠 0.25 mg から 0.125 mg へ変更後の睡眠薬の使用動向と外来患者の反応

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This survey was designed to study the recent trend in hypnotics for outpatients and their response after changing the triazolam tablet dosage from 0.25 mg to 0.125 mg. One hundred and seventy-one outpatients suffering from sleep disturbances participated in this survey, of whom seventy-four were male with a mean age of 67.5 years (range of 32-90 years), and ninety-seven were female with a mean age of 66.9 years (range of 34-89 years). The hypnotics prescribed were: triazolam, zopiclone, estazolam, brotizolam, nitrazepam, flunitrazepam and flurazepam hydrochloride. Of 91 subjects in the triazolam group, 37 were male and 54 were female. The same interviewer asked about their impression after taking 0.125 mg tablets at the dispensing counter. Although all 91 subjects were initially recruited into this survey, 17 were omitted. Of these 17, eight started taking hypnotics after changing the triazolam tablet from 0.25 mg to 0.125 mg, and nine did not take them at all. Thus, 74 subjects in the triazolam group were considered in the survey analysis. Of the 74, 62 were prescribed half doses, 11 equal doses, and only one female multiplied her dose in comparison with the formerly prescribed dose. Of these 74, 55 showed good responses and they did not express any different feeling between the two kinds of tablets. However, 19 did not receive any hyptonic effect after taking the 0.125 mg trazolam tablet. The interviewer explained the instructions for taking the medication and the side effect of hyptonics to all of hyptonics to all of them and recommend to some that they consult their doctor. Subsequently, however, he received no information of their reactions to their medication.
1994-08-20

トリアゾラム錠 0.25 mg から 0.125 mg へ変更後の睡眠薬の使用動向と外来患者の反応

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