TWO-YEAR FOLLOW UP FROM BIRTH OF THAI CHILDREN FOR ROTAVIRUS INFECTION : SEROTYPES AND RNA ELECTROPHEROTYPES

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概要

• 論文の詳細を見る

• Twenty-two group A rotavirus positive stool specimens that had been collected from 19 children in Chiang Mai, Thailand, followed up for two years from birth in 1988 to 1990 (Supawadee et al., 1995), were examined for subgrouping (I and II), and VP7 serotyping (1,2,3 and 4) by enzyme-linked immunosorbent assay (ELISA) with specific monoclonal antibodies and RNA electropherotyping by polyacrylamide gel electrophoresis (PAGE). Of these, 18 (82%) could be subgrouped (10 subgroup I and eight subgroup II) and serotyped (five serotype 1,10 serotype 2,one serotype 3 and two serotype 4). Serotype 1 virus was more predominant than type 2 during the period from January to June 1989 and type 2 was more predominant than type 1 from August 1989 to June 1990. Reinfection with rotavirus was observed in four children during the two years of the follow-up period after birth : one volunteer (No. 11) had an asymptomatic infection with serotype 2-RNA electropherotype S and a symptomatic infection with serotype 3-RNA electropherotype L. Each of the other three had asymptomatic infections twice, i.e. : one (No. 21) with serotype 1-RNA electropherotype L and undetermined serotype-RNA electropherotype L; one (No. 38) with serotype 2-RNA electropherotype S and undetermined serotype-RNA electroherotype L; and the other one (No. 23) with undetermined serotype-RNA electropherotype L and serotype 2-RNA electropherotype S. The results of 18 specimens from asymptomatic infections were compared with those of 202 specimens from symptomatic infections in the same geographical area in the same period of time and no definite relation was found between the VP7 serotype and severity of the illness.

• 日本医科大学の論文
• 1997-03-25

著者

• 鈴木 博

  Institute Of Gerontology Nippon Medical School

• SUZUKI Hiroshi

  Institute for Tropical Medicine, Nagasaki University

• 井上 栄

  Department Of Epidemiology National Institute Of Health

• INOUYE Sakae

  Department of Immunology and Infectious Disease Surveillance Center, National Institute of Infectiou

• 長谷川 斐子

  Department Of Epidemiology National Institute Of Health

• YAMAZI YUKIO

  Sayama Hakuai Hospital, International Good Will Foundation of Japan

• HASEGAWA AYAKO

  Department of Epidemiology, National Institute of Health

• SUPAWADEE JIRAPORN

  Departments of Microbiology, Family Medicine and Pediatrics, Chiang Mai University

• SUPRASERT SOMBOON

  Departments of Microbiology, Family Medicine and Pediatrics, Chiang Mai University

• RANGSIYANOND PRAPASIRI

  Departments of Microbiology, Family Medicine and Pediatrics, Chiang Mai University

• PONGPROT BOONYONG

  Departments of Microbiology, Family Medicine and Pediatrics, Chiang Mai University

• 山地 幸雄

  Sayama Hakuai Hospital, International Good Will Foundation of Japan

• 山地 幸雄

  Sayama Hakuai Hospital International Good Will Foundation Of Japan

• Inouye Sakae

  Department Of Epidemiology National Institute Of Health

• Hasegawa Ayako

  Department Of Anesthesiology University Of The Ryukyus

• Suprasert Somboon

  Departments Of Microbiology Family Medicine And Pediatrics Chiang Mai University

• Pongprot Boonyong

  Departments Of Microbiology Family Medicine And Pediatrics Chiang Mai University

• Supawadee Jiraporn

  Departments Of Microbiology Family Medicine And Pediatrics Chiang Mai University

• Rangsiyanond Prapasiri

  Departments Of Microbiology Family Medicine And Pediatrics Chiang Mai University

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