試作レジン系根管用シーラーの生体親和性(第488回大阪歯科学会例会)

概要

論文の詳細を見る
We evaluated the tissue compatibility of two newly-developed root canal sealers, one composed of 4-META/MMA-TBB resin and zirconium oxide (ZrC), and the other of 4-META/MMA-TBB resin, barium sulfate and bismuth subcar-bonate (A 4). We examined the responses of rat dorsal subcutaneous and periapical tissues to these materials. In order to examine the response in subcutaneous tissue, sections were stained with H-E for histopathological observation and with immunohistochemical stain for observation of macrophages. Serial sections were stained with H-E for histopathological observation of the periapical tissue response. The newly-developed sealers caused less subcutaneous inflammation than zinc oxide eugenol cement (the control). There was significantly less infiltration of macrophages with ZrC and A 4 compared with the control material at 4 weeks. ZrC and A 4 caused less tissue irritation in the periapical tissues than did the control material. These results indicate that both of the newly-developed root canal sealers may be useful for endodontic treatment. The one with ZrC showed especially promising results.
大阪歯科学会の論文
2003-06-25