7 Porphyromonas gingivalis外膜タンパクの分離精製および白血球に対する遊走活性 (第409回 大阪歯科学会例会)
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概要
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I purified outer membrane proteins (OMPs) of Porphyromonas gingivalis and examined their immunological activities for leukocytes. The OMPs were purified from P. gingivalis 381. SDS-PAGE analysis revealed that P. gingivalis had two main OMPs of 40kDa and 53kDa. Antibodies to both of these proteins have been observed in the sera of patients with adult periodontitis. I found that both had chemotactic activity for human monocytes and both stimulated chemotactic activity for leukocytes in cultures when they were applied to lymphocytes. However, when they were applied to macrophages, chemotactic activity appeared only in the culture stimulated with the 40kDa OMP.
- 大阪歯科学会の論文
- 1992-02-25
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関連論文
- Porphyromonas gingivalis外膜タンパクの分離精製と白血球に対する遊走活性
- Porphyromonas gingivalis外膜タンパクの分離精製と白血球に対する遊走活性
- 7 Porphyromonas gingivalis外膜タンパクの分離精製および白血球に対する遊走活性 (第409回 大阪歯科学会例会)