薬剤管理指導業務における副作用モニタリングの標準化と監査の試み : 糖尿病代謝内科および腎臓内分泌内科病棟において

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Monitoring adverse drug reactions in hospital pharmaceutical care is important in ensuring that drugs are administered safely. However, it is not efficient to uniformly monitor all adverse drug reactions for all drugs. We therefore drew up standard guidelines for the efficient monitoring of adverse drug reactions in the hospital's metabolic diseases, nephrology and endocrinology ward. As a preliminary study for this purpose, we investigated the reasons for hospitalization and medications for 302 patients to whom we provided pharmaceutical care in this ward between April 2002 and March 2003. Based on the results, 8 types of drug (sulfonylureas, α-glucosidase inhibitors, biguanides, pioglitazone, HMG-CoA reductase inhibitors, fibrates, histamine H_2 receptor antagonists, allopurinol) were selected for special monitoring and monitoring sheets were prepared for following up patients who had started to use such drugs within the last six months, and those at high risk of adverse drug reactions. Patients were monitored by 3 pharmacists who periodically audited the patients' monitoring plans. As a result of these activities, physicians accepted prescriptions proposed by our pharmacists for 9.8% of the patients, in consideration of the early detection and prevention of adverse drug reactions. Thus, our standardization of the monitoring of adverse drug reactions in hospital pharmaceutical care proved to be effective for the early detection and prevention of adverse drug reactions.
日本医療薬学会の論文
2004-12-10

薬剤管理指導業務における副作用モニタリングの標準化と監査の試み : 糖尿病代謝内科および腎臓内分泌内科病棟において

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