気管支喘息における心理的因子とchemical mediator(呼吸器心身症の病態と治療(第21回日本心身医学会総会シンポジウム))

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It is generally accepted that, in the etiology of asthma, allergic, infectious psychological, endocrinological and environmental factors interact and interdepend one another. Emotional and psychological factors play an important role at the onset and through the processes of asthma.It is the purpose of this study to elucidate the relationship between spychological factors and chemical mediators in asthmatic attacks which were induced by hypnosis.First, asthmatic patients were investigated by using the Comprehensive Asthma Inventory (abbriviated as C.A.I.), and then the hypnotical provocation test was performed. Before and after the provoked asthmatic attack, the levels of histamine and serotonin in plasma as the chemical mediators of allegic reaction were measured.The following results were obtained.1) According to the results of C.A.I., the factors related to the conditioning, suggestion and fear of expectation were observed in asthmatics.2) Out of 32 asthmatics in the hypnotical provocation test, 10 cases showed positive reactions.In the control group (healthy persons and anxiety neurosis patients), on the other hand, no one showed positive reactions.3) Before and after the hypnotical provocation test, the changes in plasma histamine and serotonin were found to be not significant.4) The plasma histamine levels tended to increase during the induced asthmatic attacks in the subject with a higher anxiety level.5) Before the hypnotical provocation test, the serotonin levels tended to increase in asthmatics and patients with anxiety neurosis who showed a severe anxious reaction.
日本心身医学会の論文
1980-10-01

気管支喘息における心理的因子とchemical mediator(呼吸器心身症の病態と治療(第21回日本心身医学会総会シンポジウム))

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