ROLE OF ADHERENT MONONUCLEAR CELLS DERIVED FROM ADULT PIGS AND SUCKLING PIGLETS IN RESPONSE TO POKEWEED MITOGEN-INDUCED IMMUNOGLOBULIN PRODUCTION
スポンサーリンク
概要
- 論文の詳細を見る
The effect of monocytes as an activator of a function of lymphocytes in pigs was studied using an in vitro Ig production system with pokeweed mitogen (PWM). When mononuclear cells (lymphocytes) from adult pigs were stimulated by PWM, optimal number of adherent cells (monocytes) collected from serum coated plastic Petri dishes were required for the generation of Ig producing cells, whereas the production was suppressed by the addition of excessive adherent cells. In neonatal and suckling piglets up to 6 weeks of age, PWM induced B lymphocyte differentiation was enhanced by addition of adherent cells from peripheral blood of adult pigs. On the other hand, adherent cells derived from piglets did not have the effect of increasing Ig production in the in vitro Ig production system with lymphocytes (non-adherent) derived from adult pigs.
- 北海道大学の論文
- 1986-10-31
著者
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Maede Yoshimitsu
北海道大学 大学院獣医科学研究科獣医内科学教室
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Maede Y
Hokkaido Univ. Sapporo Jpn
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OHSUGI Takeo
Department of Veterinary Internal Medicine, Faculty of Veterinary Medicine, Hokkaido University
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HAGIWARA Shintaroh
Depatment of Veterinary Internal Medicine, Faculty of Veterinary Medicine, Hokkaido University
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MAEDE Yoshimitsu
Depatment of Veterinary Internal Medicine, Faculty of Veterinary Medicine, Hokkaido University
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OHSUGI Takeo
Depatment of Veterinary Internal Medicine, Faculty of Veterinary Medicine, Hokkaido University
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NAMIOKA Shigeo
Depatment of Veterinary Internal Medicine, Faculty of Veterinary Medicine, Hokkaido University
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Hagiwara S
Shonan Livestock Hygiene Serv. Center Fujisawa Jpn
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