STUDIES ON "KASEN" OF HORSES IN HOKKAIDO VI : THERAPEUTIC SIGNIFICANCE OF ANTIHISTAMINE PREPARATIONS FOR HORSES AFFECTED WITH THE DISEASE

概要

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The authors have conducted practical treatment of field horses affected with "kasen" in the summer of 1957. The results thus obtained may be summarized as follows. 1. Antihistamine preparations, for instance Allergin, Hiberna, Pyribenzamin and Venacalcium B_6 were used for the treatment of "kasen" in the amount of 200〜300 mg per day for 5 days as real volume of the substances ; the cases were observed 16〜25 days after the injections. 2. Thirty-six cases out of 44 affected horses recovered completely and 6 cases relapsed despite the treatments. However, the conditions of 2 cases were unchanged in comparison with pre-treatment conditions. 3. In the recovered cases, insecticides, for instance DDT and BHC powders, were sprayed over the skin surface sufficiently, especially in the long hair areas and in the vicinity of the stables throughout the period of experiments. However in the relapsed and unchanged cases the use of insecticides was insufficient or quite neglected. 4. The values of eosinophile counts and histamine concentrations were higher in affected horses than in non-affected horses. After the patients were injected with antihistamine drugs the two constituents ran almost parallel with the variations of the clinical signs. Eosinophile numbers and histamine concentrations were increased in the relapsed cases within several days after the end of the injections.
北海道大学の論文
1958-11-15