<原著>Groggy 突然変異ラットの小脳における一過性の軸策腫大の増加

概要

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During the course of histological examination of the brains of groggy mutant rats on their different postnatal days, abrupt increases in the number of axonal swellings were observed in the lateral cerebellar nuclei of 90-day-old groggy rats. These axonal swellings were round or ellipsoidal, homogeneously eosinophilic, about 10-30μm in length, and present either in the neighborhood of neuronal cell bodies or somewhat apart from them. They tended to decrease in number from 120 days onward, but there were still limited but significant numbers of them in the lateral cerebellar nuclei of 360-day-old animals. Electron microscopic observations showed that the axonal swellings were filled with compact amorphous materials. The nature and origin of the axonal swellings were discussed.
岐阜医療科学大学の論文
1992-12-01