<Originals>Synaptophysin Accumulation in Axonal Swellings Occurring in the Cerebellar White Matter of Groggy Mutant Rats

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概要

• 論文の詳細を見る

• Axonal swellings in the cerebellar white matter of groggy mutant rats were examined with synaptophysin (SYP) immunohistochemistry at light and electron microscopic levels. The axonal swellings displayed several gradations of SYP immunostaining density at light microscopic level. Immunoelectron microscopy revealed that the axonal swellings contained various amounts of SYP-immunopositive substances which were frequently attached with small vesicles measuring about 50 nm in diameter. These results suggest that an impairment of fast axonal transport is involved in the pathogenesis of these axonal swellings, and that the SYP proteins accumulated in the swellings are digested at that place together with other cytoplasmic organelles.

• 岐阜医療科学大学の論文
• 2000-12-30

著者

• Takeuchi Yoshiko

  Gifu College Of Medical Technology

• Takeuchi Ikuo

  Institute For Developmental Research Aichi Human Service Center

関連論文

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• Age-related Appearance of Dystrophic Axon Terminals in Cerebellar and Vestibular Nuclei of Mongolian Gerbils
• ELECTRON MICROSCOPY OF THE EFFECTS OF 5-AZACYTIDINE, 50 R X-iRRADIATION, AND VINBLASTINE ON THE TELENCEPHALIC WALL OF THE RAT FETUS (The Fourth Meeting for the Study of Toxic Effect)
• Atrophy of spinal cord in groggy mutant rat
• Synaptophysin Accumulation in Axonal Swellings Occurring in the Cerebellar White Matter of Groggy Mutant Rats
• Ubiquitin Immunostaining of Axonal Swellings in Lateral Cerebellar Nuclei of Groggy Mutant Rat

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